Evidence map›Paper›PMID 32466589›Full record

ArticleInternational journal of molecular sciences2020

NanoLuc Bioluminescence-Driven Photodynamic Activation of Cholecystokinin 1 Receptor with Genetically-Encoded Protein Photosensitizer MiniSOG.

Yuan Li, Zong Jie Cui

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. To activate NAD(P)H oxidase with a brief pulse of photodynamic action.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Intracellular Ionic Strength Sensing Using NanoLuc.International journal of molecular sciences · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuan LiInstitute of Cell Biology, Beijing Normal University, Beijing 100875, China.
Zong Jie CuiInstitute of Cell Biology, Beijing Normal University, Beijing 100875, China.ORCID 0000-0003-4252-4876
Beijing Normal University · CN

Funding

The Ministry of Science and Technology of China (973 program) 2011CB809101The Natural Science Foundation of China 31670856; 31971170
6 · The paper itself

Abstract

In contrast to reversible activation by agonist, cholecystokinin 1 receptor (CCK1R) is permanently activated by singlet oxygen generated in photodynamic action, with sulphonated aluminium phthalocyanine or genetically encoded mini singlet oxygen generator (miniSOG) as photosensitizer. In these works, a halogen light source was used to power photodynamic action. For possible in vivo application of photodynamic CCK1R physiology, bearing a cumbersome light-delivery device connected to an external light source by experimental animals might interfere with their behavior. Therefore, in the present work, the possibility of bioluminescence-driven miniSOG photodynamic CCK1R activation was examined, as monitored by Fura-2 calcium imaging. In parallel experiments, it was found that, after plasma membrane (PM)-localized expression of miniSOG

Indexed as

AnimalsBiosensing TechniquesCalcium SignalingCell Line, TumorInternal Ribosome Entry SitesLightLuminescenceLuminescent ProteinsProtein EngineeringRatsReceptors, CholecystokininRecombinant ProteinsSinglet OxygenInternal Ribosome Entry SitesLuminescent ProteinsReceptors, CholecystokininRecombinant ProteinsSinglet Oxygen1O2calcium oscillationsCCK1 receptorminiSOGNanoLuc

Identifiers

PMID32466589
PMCPMC7313028
OpenAlexW3029442869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.