ReviewJournal of clinical medicine2020
Hormonal Treatment Strategies Tailored to Non-Binary Transgender Individuals.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 89 citations in OpenAlex.
- Clinician Perspectives on Gender-Affirming Medical Care of Nonbinary Youth.Transgender health · 2026Article
- Initiation and Maintenance of Low-Dose Transdermal Testosterone in Non-Binary Individuals: A Retrospective Audit.Clinical endocrinology · 2026Article
- Kidney Health and Gender-Affirming Hormone Therapy for Transgender and Gender Diverse Individuals.Clinical journal of the American Society of Nephrology : CJASN · 2026Review
- Gender-affirming health care needs, barriers to care, and health and wellbeing in a broad nationwide sample of transgender people in Norway.BMC public health · 2025Article
- Oncological needs in transgender patients.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025Review
- Individualized and innovative gender healthcare for transgender and nonbinary youth.Nature reviews. Endocrinology · 2025Review
- Principlism and contemporary ethical considerations for providers of transgender health care.International journal of transgender health · 2025Article
- Assessment of parenteral estradiol and dihydroxyprogesterone use among other feminizing regimens for transgender women: insights on satisfaction with breast development from community-based healthcare services.Annals of medicine · 2024Article
- Metabolic Features of Assigned Female at Birth Transgender People on Gender-Affirming Hormone Therapy: A Meta-analysis.Transgender health · 2024Review
- Efficacy of topical minoxidil in enhancing beard growth in a group of transgender assigned female at birth individuals on gender affirming hormone therapy.Journal of endocrinological investigation · 2024Article
- A Mouse Model to Investigate the Impact of Gender Affirming Hormone Therapy with Estradiol on Reproduction.Advanced biology · 2024Article
- Endometriosis in Transgender Men: Bridging Gaps in Research and Care-A Narrative Review.Biomedicines · 2024Review
- Pediatric Gender Diversity Beyond the Binary: An Exploration of Gender-Affirming Care for Nonbinary and Genderqueer Youth Seen Over Time at a Single Institution Gender Center.Transgender health · 2024Article
- Sublingual Estradiol Offers No Apparent Advantage Over Combined Oral Estradiol and Cyproterone Acetate for Gender-Affirming Hormone Therapy of Treatment-Naive Trans Women: Results of a Prospective Pilot Study.Transgender health · 2023Article
- Tailored Gender-Affirming Hormone Treatment in Nonbinary Transgender Individuals: A Retrospective Study in a Referral Center Cohort.Transgender health · 2023Article
- Effects of hormonal treatment on dermatological outcome in transgender people: a multicentric prospective study (ENIGI).Journal of endocrinological investigation · 2023Article
- Body image and treatment desires at clinical entry in non-binary and genderqueer adults.International journal of transgender health · 2023Article
- Gender-affirming endocrine care for youth with a nonbinary gender identity.Therapeutic advances in endocrinology and metabolism · 2023Review
- Medical considerations in the care of transgender and gender diverse patients with eating disorders.Journal of eating disorders · 2022Review
- Review of Health Insurance Policy Inclusivity of Gender Nonconforming and Nonbinary Individuals Seeking Gender-Affirming Health Care.Transgender health · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionTo date no standardized hormonal treatment protocols for non-binary transgender individuals have been described in the literature and there is a lack of data regarding their efficacy and safety.
objectivesTo suggest possible treatment strategies for non-binary transgender individuals with non-standardized requests and to emphasize the importance of a personalized clinical approach.
methodsA narrative review of pertinent literature on gender-affirming hormonal treatment in transgender persons was performed using PubMed.
resultsNew hormonal treatment regimens outside those reported in current guidelines should be considered for non-binary transgender individuals, in order to improve psychological well-being and quality of life. In the present review we suggested the use of hormonal and non-hormonal compounds, which-based on their mechanism of action-could be used in these cases depending on clients' requests.
conclusionRequests for an individualized hormonal treatment in non-binary transgender individuals represent a future challenge for professionals managing transgender health care. For each case, clinicians should balance the benefits and risks of a personalized non-standardized treatment, actively involving the person in decisions regarding hormonal treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.