Trial reportInternational journal of environmental research and public health2020
Multicomponent Exercise Program Reduces Frailty and Inflammatory Biomarkers and Improves Physical Performance in Community-Dwelling Older Adults: A Randomized Controlled Trial.
Trial report in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07572851 (Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care), which is not on this map. Cited by 95 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care
Who cites it
95 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Effects of exercise interventions on inflammatory biomarker levels in older adults with frailty and/or sarcopenia: a systematic review and meta-analysis.Frontiers in immunology · 2026Pooled it
- Effects of exercise with music in frail older adults: a systematic review and meta-analysis.BMJ open · 2025Pooled it
- Meta-analysis of the effects of multi-component exercise on cognitive function in older adults with cognitive impairment.Frontiers in aging neuroscience · 2025Pooled it
- Impact of multicomponent exercise and nutritional supplement interventions for improving physical frailty in community-dwelling older adults: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Association between pre-stroke frailty status and stroke risk and impact on outcomes: a systematic review and meta-analysis of 1,660,328 participants.Aging clinical and experimental research · 2024Pooled it
- Community-based exercises improve health status in pre-frail older adults: A systematic review with meta-analysis.BMC geriatrics · 2024Pooled it
- The changes of blood-based inflammatory biomarkers after non-pharmacologic interventions for chronic low back pain: a systematic review.BMC musculoskeletal disorders · 2024Pooled it
- Multidomain interventions for sarcopenia and cognitive flexibility in older adults for promoting healthy aging: a systematic review and meta-analysis of randomized controlled trials.Aging clinical and experimental research · 2024Pooled it
- Rhythmic Physical Activity and Global Cognition in Older Adults with and without Mild Cognitive Impairment: A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Influence of a Multicomponent Supervised Exercise Program on Frail and Prefrail Community-Dwelling Older Adults: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2026Trial
- Long-term frailty and physical performance transitions in older people with type-2 diabetes. The MIDFRAIL randomized clinical study.The journal of nutrition, health & aging · 2025Trial
- Effects of Different Exercise Interventions on Fall Risk and Gait Parameters in Frail Patients After Open Heart Surgery: A Pilot Study.Medicina (Kaunas, Lithuania) · 2025Trial
- Functional mobility and physical fitness are improved through a multicomponent training program in institutionalized older adults.GeroScience · 2024Trial
- Frailty-Preventing Effect of an Intervention Program Using a Novel Complete Nutritional "COMB-FP Meal": A Pilot Randomized Control Trial.Nutrients · 2023Trial
- Multicomponent Training in Progressive Phases Improves Functional Capacity, Physical Capacity, Quality of Life, and Exercise Motivation in Community-Dwelling Older Adults: A Randomized Clinical Trial.International journal of environmental research and public health · 2023Trial
- Impact of adapted taekwondo vs. multicomponent training on health status in independent older women: a randomized controlled trial.Frontiers in public health · 2023Trial
- Effects of Adding an Online Exercise Program on Physical Function in Individuals Hospitalized by COVID-19: A Randomized Controlled Trial.International journal of environmental research and public health · 2022Trial
- Feasibility, acceptability, and preliminary effects of the Join4Joy approach for older adults living in nursing homes: a multicentre mixed-methods feasibility study.European geriatric medicine · 2026Article
- Effect of bodyweight interval training on frailty status in older adults: a randomized controlled trial.European geriatric medicine · 2026Article
- Supervised Exercise Intervention Restores Physical Activity and MultiOMIC-Derived Frailty Biomarkers in Older Adults.Journal of cachexia, sarcopenia and muscle · 2026Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The efficacy of exercise to reverse frailty in the aging population has not been extensively investigated. This study aimed to investigate the effectiveness of a multicomponent exercise program (MCEP) on frailty, physical performance (handgrip strength, Berg Balance Scale (BBS), Timed Up and Go test (TUG), and VO
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.