Evidence map›Paper›PMID 32466371›Full record

ArticleAntibiotics (Basel, Switzerland)2020

The Pharmaceutical Ability of

Egle Milia, Marianna Usai, Barbora Szotáková, Marie Elstnerová, Věra Králová, Guy D'hallewin, Ylenia Spissu, Antonio Barberis, Mauro Marchetti, Antonella Bortone and 4 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Antimicrobial Efficiency ofMicroorganisms · 2023
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Leaves and Fruits Preparations ofAntibiotics (Basel, Switzerland) · 2021
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Egle MiliaSurgery and Experimental Science, Department of Medicine, University of Sassari, Viale San Pietro 43, 07100 Sassari, Italy.ORCID 0000-0002-4272-0538
Marianna UsaiDepartment of Chemistry and Pharmacy, University of Sassari, Via Rolando, 07100 Sassari, Italy.
Barbora SzotákováFaculty of Pharmacy, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.ORCID 0000-0002-0377-0743
Marie ElstnerováFaculty of Pharmacy, Charles University, Akademika Heyrovského 1203, 50005 Hradec Králové, Czech Republic.
Věra KrálováFaculty of Medicine, Charles University, Šimkova 870, 50003 Hradec Králové, Czech Republic.
Guy D'hallewinNational Research Council - Institute of Sciences of Food Production, Traversa La Crucca 3, Loc. Baldinca, 07100 Sassari, Italy.
Ylenia SpissuNational Research Council - Institute of Sciences of Food Production, Traversa La Crucca 3, Loc. Baldinca, 07100 Sassari, Italy.ORCID 0000-0003-1551-8817
Antonio BarberisNational Research Council - Institute of Sciences of Food Production, Traversa La Crucca 3, Loc. Baldinca, 07100 Sassari, Italy.ORCID 0000-0002-7948-0822
Mauro MarchettiNational Research Council - Institute of Biomolecular Chemistry, Traversa La Crucca 3, Loc. Baldinca, 07100 Sassari, Italy.
Antonella BortoneDental Unite, Department of Surgery, Azienda Ospedaliero Universitaria, 07100 Sassari, Italy.
Vincenzo CampanellaDepartment of Clinical and Translational Medicine, University of Rome, Tor Vergata, 00133 Rome, Italy.
Giorgio MastandreaDepartment of Biomedical Science, University of Sassari, Viale San Pietro 43/C, 07100 Sassari, Italy.
Lenka LanghansováInstitute of Experimental Botany, Czech Academy of Sciences, Rozvojová 263, 16502 Prague, Czech Republic.
Sigrun EickDepartment of Periodontology, School of Dental Medicine, University of Bern, Freiburgstrasse 7, 3010 Bern, Switzerland.ORCID 0000-0002-4619-2461

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the increasing request for natural pharmacological molecules, this study assessed the antimicrobial capacity of Pistacia lentiscus L. essential oil (PLL-EO) obtained from the leaves of wild plants growing in North Sardinia (Italy) toward a wide range of periodontal bacteria and

methodsPLL-EO was screened by gas chromatography/mass spectrometry. The minimal inhibitory concentration (MIC) was determined. The anti-inflammatory activity was measured by cyclooxygenase (COX-1/2) and lipoxygenase (LOX) inhibition, while the antioxidant capacity was determined electro-chemically and by the MTT assay. The WST-1 assay was used to ascertain cytotoxicity toward four lines of oral cells.

resultsAccording to the concentrations of terpens, PLL-EO is a pharmacologically-active phytocomplex. MICs against periodontal bacteria ranged between 3.13 and 12.5 µg/ml, while against

conclusionsPLL-EO exhibits a broad-spectrum activity against periodontal bacteria and

Indexed as

Candida albicansCandida glabratacyclooxygenaselipoxygenasemedicinal herbsOral health care productsperiodontal disease

Identifiers

PMID32466371
PMCPMC7345856

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.