Evidence map›Paper›PMID 32466323›Full record

ArticleSensors (Basel, Switzerland)2020

Characterisation of Ex Vivo Liver Thermal Properties for Electromagnetic-Based Hyperthermic Therapies.

Nuno P Silva, Anna Bottiglieri, Raquel C Conceição, Martin O'Halloran, Laura Farina

Open access · goldAbstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 47 citations in OpenAlex.

  1. Integrating temperature-dependent tissue properties into focused ultrasound computational models for enhanced treatment planning.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2026
    Article
  2. Closing the Loop: High-Precision 3D Photofabrication in Living Tissues.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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  5. Simulation of Image-Guided Microwave Ablation Therapy Using a Digital Twin Computational Model.IEEE open journal of engineering in medicine and biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nuno P SilvaTranslational Medical Device Lab, National University of Ireland Galway, H91 TK33 Galway, Ireland.ORCID 0000-0003-0015-8951
Anna BottiglieriTranslational Medical Device Lab, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Raquel C ConceiçãoInstituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências Universidade de Lisboa, 1749-016 Lisbon, Portugal.ORCID 0000-0002-0025-863X
Martin O'HalloranTranslational Medical Device Lab, National University of Ireland Galway, H91 TK33 Galway, Ireland.
Laura FarinaTranslational Medical Device Lab, National University of Ireland Galway, H91 TK33 Galway, Ireland.ORCID 0000-0002-1571-8037
Ollscoil na Gaillimhe – University of Galway · IEUniversity of Lisbon · PT

Funding

Erasmus+ 46899 269558-EPP-1-2015-1-PT-EPPKA3-ECHE - P LISBOA109Fundação para a Ciência e a Tecnologia-FCT, FCT/MEC (PIDDAC) Strategic Programme UIDB/00645/2020H2020 European Research Council 637780H2020 Marie Skłodowska-Curie Actions 713690Science Foundation Ireland 13/RC/2073
6 · The paper itself

Abstract

Electromagnetic-based hyperthermic therapies induce a controlled increase of temperature in a specific tissue target in order to increase the tissue perfusion or metabolism, or even to induce cell necrosis. These therapies require accurate knowledge of dielectric and thermal properties to optimise treatment plans. While dielectric properties have been well investigated, only a few studies have been conducted with the aim of understanding the changes of thermal properties as a function of temperature; i.e., thermal conductivity, volumetric heat capacity and thermal diffusivity. In this study, we experimentally investigate the thermal properties of ex vivo ovine liver in the hyperthermic temperature range, from 25 °C to 97 °C. A significant increase in thermal properties is observed only above 90 °C. An analytical model is developed to model the thermal properties as a function of temperature. Thermal properties are also investigated during the natural cooling of the heated tissue. A reversible phenomenon of the thermal properties is observed; during the cooling, thermal properties followed the same behaviour observed in the heating process. Additionally, tissue density and water content are evaluated at different temperatures. Density does not change with temperature; mass and volume losses change proportionally due to water vaporisation. A 30% water loss was observed above 90 °C.

Indexed as

Electromagnetic PhenomenaHyperthermia, InducedLiverTemperatureAnimalsHot TemperatureSheepdensityelectromagnetic-based therapieshyperthermiathermal ablationthermal propertieswater loss

Identifiers

PMID32466323
PMCPMC7285484
OpenAlexW3028133929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.