Evidence map›Paper›PMID 32466318›Full record

ArticleMolecules (Basel, Switzerland)2020

Experimental Data Based Machine Learning Classification Models with Predictive Ability to Select in Vitro Active Antiviral and Non-Toxic Essential Oils.

Manuela Sabatino, Marco Fabiani, Mijat Božović, Stefania Garzoli, Lorenzo Antonini, Maria Elena Marcocci, Anna Teresa Palamara, Giovanna De Chiara, Rino Ragno

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Molecules (Basel, Switzerland) · 2026
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  4. Review
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  11. Molecules (Basel, Switzerland) · 2022
    Article
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  13. Frontiers in microbiology · 2022
    Article
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manuela SabatinoRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.
Marco FabianiDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, 00161 Rome, Italy.ORCID 0000-0002-8763-0114
Mijat BožovićUniversity of Montenegro, Faculty of Science and Mathematics, Džordža Vašingtona bb, 81000 Podgorica, Montenegro.
Stefania GarzoliDepartment of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0001-8535-0533
Lorenzo AntoniniRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.
Maria Elena MarcocciDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, 00161 Rome, Italy.ORCID 0000-0003-4751-4263
Anna Teresa PalamaraDepartment of Public Health and Infectious Diseases, Sapienza University of Rome, Laboratory affiliated to Istituto Pasteur Italia-Fondazione Cenci Bolognetti, 00161 Rome, Italy.ORCID 0000-0001-8330-4381
Giovanna De ChiaraInstitute of Translational Pharmacology, National Research Council, 00133 Rome, Italy.ORCID 0000-0002-2219-6097
Rino RagnoRome Center for Molecular Design, Department of Drug Chemistry and Technology, Sapienza University, P.le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0001-5399-975X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decade essential oils have attracted scientists with a constant increase rate of more than 7% as witnessed by almost 5000 articles. Among the prominent studies essential oils are investigated as antibacterial agents alone or in combination with known drugs. Minor studies involved essential oil inspection as potential anticancer and antiviral natural remedies. In line with the authors previous reports the investigation of an in-house library of extracted essential oils as a potential blocker of HSV-1 infection is reported herein. A subset of essential oils was experimentally tested in an in vitro model of HSV-1 infection and the determined IC

Indexed as

AnimalsAntiviral AgentsChlorocebus aethiopsGas Chromatography-Mass SpectrometryHerpesvirus 1, HumanHumansLamialesMicrobial Sensitivity TestsOils, VolatilePlant OilsStructure-Activity RelationshipSupervised Machine LearningVero CellsAntiviral AgentsOils, VolatilePlant Oilsclassification modelingessential oilherpes simplex virusmachine learningmultidisciplinary applicationPLS-DAQCARquantitative composition-activity relationships

Identifiers

PMID32466318
PMCPMC7288128

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.