Evidence map›Paper›PMID 32466286›Full record

ArticleBiomolecules2020

Reduced Reverse Cholesterol Transport Efficacy in Healthy Men with Undesirable Postprandial Triglyceride Response.

Alexandre Motte Motte, Julie Gall Gall, Joe-Elie Salem, Eric Dasque, Martine Lebot, Eric Frisdal, Sophie Galier, Elise F Villard, Elodie Bouaziz-Amar, Jean-Marc Lacorte and 4 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03109067 (Influence of TaqIB), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03109067 nacompletednot on this map

Influence of TaqIB (rs708272) Polymorphism in Cholesteryl Ester Transfer Protein (CETP) Gene on Functionality of HDL Particles, in the Pathway of Reverse Transport of Fasting and Post-prandial Cholesterol.

TypeinterventionalSponsorInstitut National de la Santé Et de la Recherche Médicale, FranceRan2011 to 2015Enrolled100ConditionsHealthy VolunteersArmsStandardized meal
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  5. Hippocampal BMP signaling as a common pathway for antidepressant action.Cellular and molecular life sciences : CMLS · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Alexandre Motte MotteResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Julie Gall GallResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Joe-Elie SalemResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Eric DasqueCentre d'Investigation Clinique Paris-Est CIC-1901 Hôpital de la Pitié-Salpêtrière AP-HP, 75013 Paris, France.
Martine LebotCentre d'Investigation Clinique Paris-Est CIC-1901 Hôpital de la Pitié-Salpêtrière AP-HP, 75013 Paris, France.
Eric FrisdalResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Sophie GalierResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Elise F VillardResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Elodie Bouaziz-AmarResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Jean-Marc LacorteResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Beny CharbitCentre d'Investigation Clinique Paris-Est CIC-1901 Hôpital de la Pitié-Salpêtrière AP-HP, 75013 Paris, France.
Wilfried Le GoffResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Philippe LesnikResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.
Maryse GuerinResearch Institute of Cardiovascular Disease, Metabolism and Nutrition, Faculté de Médecine - Hôpital Pitié-Salpêtrière, Sorbonne University, Inserm, UMR_S1166-ICAN, F-75013 Paris, France.ORCID 0000-0003-0150-1360
Inserm · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Elevation of nonfasting triglyceride (TG) levels above 1.8 g/L (2 mmol/L) is associated with increased risk of cardiovascular diseases. Exacerbated postprandial hypertriglyceridemia (PP-HTG) and metabolic context both modulate the overall efficacy of the reverse cholesterol transport (RCT) pathway, but the specific contribution of exaggerated PP-HTG on RCT efficacy remains indeterminate. Healthy male volunteers (

Indexed as

Postprandial PeriodAdultCholesterolCholesterol EstersCholesterol Ester Transfer ProteinsChylomicronsHumansHypertriglyceridemiaLipoproteins, HDLLiverMacrophagesMaleTriglyceridesCETP protein, humanCholesterolCholesterol EstersCholesterol Ester Transfer ProteinsChylomicronsHDL cholesteryl esterLipoproteins, HDLTriglyceridesCETPcholesterol effluxhigh-density lipoproteinhypertriglyceridemiamacrophagepostprandialreverse cholesterol transporttriglyceride-rich lipoprotein

Identifiers

PMID32466286
PMCPMC7277968
OpenAlexW3027877575

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.