Evidence map›Paper›PMID 32466222›Full record

ArticleInternational journal of molecular sciences2020

RNAs in Brain and Heart Diseases.

Dimitris Beis, Inga Zerr, Fabio Martelli, Wolfram Doehner, Yvan Devaux

Open access · goldAbstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Unveiling the Multifaceted Problems Associated with Dysrhythmia.International journal of molecular sciences · 2023
    Review
  5. Review
  6. (Epi)transcriptomics in cardiovascular and neurological complications of COVID-19.Journal of molecular and cellular cardiology plus · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 4 countries.

Dimitris BeisZebrafish Disease Models lab, Center for Experimental Surgery Clinical and Translational Research, Biomedical Research Foundation Academy of Athens, 11527 Athens, Greece.ORCID 0000-0003-2579-7848
Inga ZerrDepartment of Neurology, Clinical Dementia Centre and DZNE, University Medical School, Georg-August University, 37075 Göttingen, Germany.ORCID 0000-0002-6722-2463
Fabio MartelliMolecular Cardiology Laboratory, IRCCS Policlinico San Donato, San Donato Milanese, 20097 Milan, Italy.ORCID 0000-0002-8624-7738
Wolfram DoehnerDepartment of Cardiology (Virchow Klinikum), BIH-Center for Regenerative Therapies, and Center for Stroke Research Berlin Charité-Universitätsmedizin, 13353 Berlin, Germany.
Yvan DevauxCardiovascular Research Unit, Department of Population Health, Luxembourg Institute of Health, L-1445 Strassen, Luxembourg.ORCID 0000-0002-5321-8543
Academy of Athens · GRCharité - Universitätsmedizin Berlin · DEIRCCS Policlinico San Donato · ITLuxembourg Institute of Health · LUUniversity of Göttingen · DE

Funding

COST (European Cooperation in Science and Technology) Action EU-CardioRNA CA17129Fonds National de la Recherche Luxembourg C14/BM/8225223Fonds National de la Recherche Luxembourg C17/BM/11613033Heart Foundation - Daniel Wagner naMinistero della Salute 5x1000Ministero della Salute Ricerca CorrenteMinistry of Higher Education and Research of Luxembourg naTelethon Foundation GGP19035A
6 · The paper itself

Abstract

In the era of single-cell analysis, one always has to keep in mind the systemic nature of various diseases and how these diseases could be optimally studied. Comorbidities of the heart in neurological diseases as well as of the brain in cardiovascular diseases are prevalent, but how interactions in the brain-heart axis affect disease development and progression has been poorly addressed. Several brain and heart diseases share common risk factors. A better understanding of the brain-heart interactions will provide better insights for future treatment and personalization of healthcare, for heart failure patients' benefit notably. We review here emerging evidence that studying noncoding RNAs in the brain-heart axis could be pivotal in understanding these interactions. We also introduce the Special Issue of the International Journal of Molecular Sciences RNAs in Brain and Heart Diseases-EU-CardioRNA COST Action.

Indexed as

AnimalsBiomarkersBrain DiseasesCell-Free Nucleic AcidsHeart DiseasesHumansRNA, UntranslatedSignal TransductionBiomarkersCell-Free Nucleic AcidsRNA, Untranslatedbraincomorbiditiesheartneurocardiologynoncoding RNAs

Identifiers

PMID32466222
PMCPMC7279324
OpenAlexW3028003497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.