Evidence map›Paper›PMID 32466217›Full record

ArticleCancers2020

Genomic and Transcriptomic Characteristics According to Size of Papillary Thyroid Microcarcinoma.

Young Shin Song, Byung-Hee Kang, Seungbok Lee, Seong-Keun Yoo, Young Sik Choi, Jungsun Park, Dong Yoon Park, Kyu Eun Lee, Jeong-Sun Seo, Young Joo Park

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

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  14. Actualities in genetics of differentiated thyroid cancer.Acta endocrinologica (Bucharest, Romania : 2005)
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Young Shin SongDepartment of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam 13496, Korea.ORCID 0000-0003-4603-1999
Byung-Hee KangDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.
Seungbok LeeDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.
Seong-Keun YooHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Young Sik ChoiDepartment of Internal Medicine, Kosin University College of Medicine, Busan 49267, Korea.ORCID 0000-0002-7583-1816
Jungsun ParkData Labs, SK Telecom, Seoul 04539, Korea.ORCID 0000-0002-3670-7820
Dong Yoon ParkData Labs, SK Telecom, Seoul 04539, Korea.
Kyu Eun LeeDepartment of Surgery, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-2354-3599
Jeong-Sun SeoDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea.
Young Joo ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea.ORCID 0000-0002-3671-6364
Seoul National University · KRSK Group (South Korea) · KRCHA University Bundang Medical Center · KRKosin University · KRMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Ministry of Science and ICT, South Korea NRF-2019R1A2C2084332Ministry of Science and ICT, South Korea NRF-2020R1C1C1003924NCI NIH HHS P30 CA008748SK Telecom 2012-2013
6 · The paper itself

Abstract

It is controversial as to whether papillary thyroid microcarcinoma (PTMC) has some genomic and transcriptomic characteristics that differentiate between an early-stage lesion that would eventually evolve into the larger papillary thyroid cancer (PTC), and an occult indolent cancer in itself. To investigate this, we comprehensively elucidated the genomic and transcriptomic landscapes of PTMCs of different sizes, using a large-scaled database. This study included 3435 PTCs, 1985 of which were PTMCs. We performed targeted next-generation sequencing for 221 PTCs and integrated these data with the data including The Cancer Genome Atlas (TCGA) project. The frequency of v-raf murine sarcoma viral oncogene homolog B (

Indexed as

genomemassively parallel sequencingmolecular characteristicspapillary thyroid microcarcinomatranscriptometumor size

Identifiers

PMID32466217
PMCPMC7281223
OpenAlexW3027520774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.