Evidence map›Paper›PMID 32466188›Full record

ArticleCancers2020

Genetic Analysis Reveals a Significant Contribution of

Chien-Chih Ke, Lih-Chyang Chen, Chia-Cheng Yu, Wei-Chung Cheng, Chao-Yuan Huang, Victor C Lin, Te-Ling Lu, Shu-Pin Huang, Bo-Ying Bao

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. From Plastics to Prognosis:Diagnostics (Basel, Switzerland) · 2026
    Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Genetic Analysis Implicates Dysregulation ofInternational journal of environmental research and public health · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Genetic Analysis Identifies the Role ofCancer genomics & proteomics
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Chien-Chih KeDepartment of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Lih-Chyang ChenDepartment of Medicine, Mackay Medical College, New Taipei City 252, Taiwan.
Chia-Cheng YuDivision of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.
Wei-Chung ChengGraduate Institute of Biomedical Sciences, China Medical University, Taichung 404, Taiwan.
Chao-Yuan HuangDepartment of Urology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Victor C LinDepartment of Urology, E-Da Hospital, Kaohsiung 824, Taiwan.
Te-Ling LuDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan.ORCID 0000-0003-1408-6004
Shu-Pin HuangDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.ORCID 0000-0003-2968-6125
Bo-Ying BaoDepartment of Pharmacy, China Medical University, Taichung 404, Taiwan.ORCID 0000-0001-5510-6513
China Medical University · TWKaohsiung Medical University · TWAsia University · TWE-Da Hospital · TWMackay Medical University · TWNational Taiwan University Hospital · TWNational Yang Ming Chiao Tung University · TW

Funding

China Medical University, Taiwan CMU107-S-42China Medical University, Taiwan CMU108-MF-50China Medical University, Taiwan CMU108-SR-121Kaohsiung Medical University Chung-Ho Memorial Hospital KMUH108-8R53Kaohsiung Medical University Chung-Ho Memorial Hospital KMUH108-8R55Kaohsiung Medical University Research Center KMU-TC108A04-4Kaohsiung Medical University Research Foundation KMU-Q108018Kaohsiung Medical University Research Foundation KMU-Q109004Ministry of Science and Technology, Taiwan 108-2314-B-037-015Ministry of Science and Technology, Taiwan 108-2314-B-037-026-MY2Ministry of Science and Technology, Taiwan 108-2314-B-037-029Ministry of Science and Technology, Taiwan 108-2320-B-039-050-MY3Ministry of Science and Technology, Taiwan 108-2813-C-039-148-B
6 · The paper itself

Abstract

The genes that influence prostate cancer progression remain largely unknown. Since the carboxylesterase gene family plays a crucial role in xenobiotic metabolism and lipid/cholesterol homeostasis, we hypothesize that genetic variants in carboxylesterase genes may influence clinical outcomes for prostate cancer patients. A total of 478 (36 genotyped and 442 imputed) single nucleotide polymorphisms (SNPs) in five genes of the carboxylesterase family were assessed in terms of their associations with biochemical recurrence (BCR)-free survival in 643 Taiwanese patients with prostate cancer who underwent radical prostatectomy. The strongest association signal was shown in

Indexed as

biomarkercarboxylesteraseprognosisprogressionprostate cancer

Identifiers

PMID32466188
PMCPMC7281132
OpenAlexW3028252707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.