Evidence map›Paper›PMID 32466118›Full record

ArticleJournal of cardiovascular development and disease2020

Catherine A Stothard, Silvia Mazzotta, Arjun Vyas, Jurgen E Schneider, Timothy J Mohun, Deborah J Henderson, Helen M Phillips, Simon D Bamforth

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Molecular Pathways and Animal Models of Truncus Arteriosus.Advances in experimental medicine and biology · 2024
    Review
  5. Review
  6. Review
  7. PAX Genes in Cardiovascular Development.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Early Embryonic Expression ofJournal of cardiovascular development and disease · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Catherine A StothardNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Silvia MazzottaNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Arjun VyasNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Jurgen E SchneiderBiomedical Imaging, University of Leeds, Leeds LS2 9JT, UK.
Timothy J MohunThe Francis Crick Institute, London NW1 1AT, UK.
Deborah J HendersonNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Helen M PhillipsNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Simon D BamforthNewcastle University Biosciences Institute, Centre for Life, Newcastle-upon-Tyne NE1 3BZ, UK.
Centre for Life · GBThe Francis Crick Institute · GBUniversity of Leeds · GB

Funding

British Heart Foundation FS/11/50/29038British Heart Foundation FS/16/8/31984British Heart Foundation PG/16/39/32115British Heart Foundation RG/12/15/29935British Heart Foundation RG/19/2/34256
6 · The paper itself

Abstract

The correct formation of the aortic arch arteries depends on a coordinated and regulated gene expression profile within the tissues of the pharyngeal arches. Perturbation of the gene regulatory networks in these tissues results in congenital heart defects affecting the arch arteries and the outflow tract of the heart. Aberrant development of these structures leads to interruption of the aortic arch and double outlet right ventricle, abnormalities that are a leading cause of morbidity in 22q11 Deletion Syndrome (DS) patients. We have recently shown that

Indexed as

arch arteriesGbx2Pax9pharyngeal endodermTbx1

Identifiers

PMID32466118
PMCPMC7344924
OpenAlexW3027775069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.