Evidence map›Paper›PMID 32466116›Full record

ArticlePharmaceutics2020

Photoactivatable Surface-Functionalized Diatom Microalgae for Colorectal Cancer Targeted Delivery and Enhanced Cytotoxicity of Anticancer Complexes.

Joachim Delasoie, Philippe Schiel, Sandra Vojnovic, Jasmina Nikodinovic-Runic, Fabio Zobi

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 44 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Modification of Living Diatom,ACS applied bio materials · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Joachim DelasoieDepartment of Chemistry, Fribourg University, Chemin du Musée 9, 1700 Fribourg, Switzerland.ORCID 0000-0002-2633-5074
Philippe SchielDepartment of Chemistry, Fribourg University, Chemin du Musée 9, 1700 Fribourg, Switzerland.
Sandra VojnovicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia.
Jasmina Nikodinovic-RunicInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, Serbia.ORCID 0000-0002-2553-977X
Fabio ZobiDepartment of Chemistry, Fribourg University, Chemin du Musée 9, 1700 Fribourg, Switzerland.ORCID 0000-0002-9077-7184
University of Fribourg · CHUniversity of Belgrade · RS

Funding

Ministry of Education, Science and Technological Development of the Republic of Serbia 173048Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung PP00P2_170589
6 · The paper itself

Abstract

Systemic toxicity and severe side effects are commonly associated with anticancer chemotherapies. New strategies based on enhanced drug selectivity and targeted delivery to cancer cells while leaving healthy tissue undamaged can reduce the global patient burden. Herein, we report the design, synthesis and characterization of a bio-inspired hybrid multifunctional drug delivery system based on diatom microalgae. The microalgae's surface was chemically functionalized with hybrid vitamin B

Indexed as

cancercarbon monoxide releasing moleculediatomsdrug delivery systemHCT-116porphyrinrheniumvitamin B12

Identifiers

PMID32466116
PMCPMC7285135
OpenAlexW3027802746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.