Evidence map›Paper›PMID 32464573›Full record

ArticleThe Science of the total environment2020

Ambient particle radioactivity and gestational diabetes: A cohort study of more than 1 million pregnant women in Massachusetts, USA.

Stefania Papatheodorou, Diane R Gold, Annelise J Blomberg, Michele Hacker, Blair J Wylie, Weeberb J Requia, Emily Oken, Abby F Fleisch, Joel D Schwartz, Petros Koutrakis

Open access · greenAbstract read
In one paragraph

Article in The Science of the total environment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Ambient PM gross β-activity and glucose levels during pregnancy.Environmental health : a global access science source · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Stefania PapatheodorouDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: spapathe@hsph.harvard.edu.
Diane R GoldDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital Harvard Medical School, Boston, MA 02115, USA.
Annelise J BlombergDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Michele HackerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Blair J WylieDivision of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Weeberb J RequiaDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.
Abby F FleischPediatric Endocrinology and Diabetes, Maine Medical Center, Portland, ME, USA; Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, ME, USA.
Joel D SchwartzDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Petros KoutrakisDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Harvard University · USBeth Israel Deaconess Medical Center · USBrigham and Women's Hospital · USMaine Medical Center · US

Funding

Prospective associations of childhood PFAS with metabolomic profiles, pubertal timing, and bone healthR01ES030101 · NIEHS · MAINEHEALTH · PI Abby Fleisch · 2019 to 2026
$3.6M
Air Pollution Exposure during Pregnancy, Maternal Glycemia, and OffspringGrowthK23ES024803 · NIEHS · MAINEHEALTH · PI FLEISCH, ABBY · 2015 to 2019
$835k
EPA R835872C001NIEHS NIH HHS K23 ES024803NIEHS NIH HHS R01 ES030101
6 · The paper itself

Abstract

backgroundExposure to ionizing radiation increases the risk of chronic metabolic disorders such as insulin resistance and type 2 diabetes. Internal ionizing radiation from inhaled radioactive aerosol may contribute to the associations between fine particulate matter (PM

methodsWe used the Massachusetts Registry of Vital Records to study 1,061,937 pregnant women from 2001 to 2015 with a singleton pregnancy without pre-existing diabetes. Gross β activity measured by seven monitors of the U.S. Environmental Protection Agency's RadNet monitoring network was utilized to represent ambient particle radioactivity (PR). We obtained GDM status from birth certificates and used logistic regression analyses adjusted for socio-demographics, maternal comorbidities, PM

resultsAmbient particle radioactivity exposure during first and second trimester of pregnancy was associated with higher odds of GDM (OR: 1.18 (95% CI 1.10 to 1.22). Controlling for PM

conclusionThis is the first population-based study to examine the association between particle radioactivity and gestational diabetes mellitus - one of the most common pregnancy-related diseases with lifelong effects for the mother and the fetus. This finding has important public health policy implications because it enhances our understanding about the toxicity of PR, a modifiable risk factor, which to date, has been considered only as an indoor and occupational air quality risk.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2RadioactivityAir PollutantsCohort StudiesFemaleHumansMassachusettsParticulate MatterPregnancyUnited StatesAir PollutantsParticulate MatterAir pollutionGestational diabetesParticle radioactivity

Identifiers

PMID32464573
PMCPMC7472683
OpenAlexW3024049113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.