Evidence map›Paper›PMID 32464047›Full record

ArticleACS applied materials & interfaces2020

Highly Reproducible Hyperthermia Response in Water, Agar, and Cellular Environment by Discretely PEGylated Magnetite Nanoparticles.

Idoia Castellanos-Rubio, Irati Rodrigo, Ane Olazagoitia-Garmendia, Oihane Arriortua, Izaskun Gil de Muro, José S Garitaonandia, Jose Ramón Bilbao, M Luisa Fdez-Gubieda, Fernando Plazaola, Iñaki Orue and 2 more

Open access · greenAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 54 citations in OpenAlex.

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  16. Tailoring mSiOFrontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Idoia Castellanos-RubioDepartamento de Química Inorgánica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.ORCID http://orcid.org/0000-0003-4525-4883
Irati RodrigoDepartment of Electricidad y Electrónica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
Ane Olazagoitia-GarmendiaDepartamento de Genética, Antropología Física y Fisiología Animal, Facultad de Medicina y Enfermerı́a, Barrio Sarriena s/n, 48940, Leioa, Spain.
Oihane ArriortuaDepartamento de Química Inorgánica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
Izaskun Gil de MuroDepartamento de Química Inorgánica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
José S GaritaonandiaDepartamento de Física Aplicada II, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
Jose Ramón BilbaoDepartamento de Genética, Antropología Física y Fisiología Animal, Facultad de Medicina y Enfermerı́a, Barrio Sarriena s/n, 48940, Leioa, Spain.
M Luisa Fdez-GubiedaDepartment of Electricidad y Electrónica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.ORCID http://orcid.org/0000-0001-6076-7738
Fernando PlazaolaDepartment of Electricidad y Electrónica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
Iñaki OrueSGIker, Servicios Generales de Investigación, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
Ainara Castellanos-RubioDepartamento de Genética, Antropología Física y Fisiología Animal, Facultad de Medicina y Enfermerı́a, Barrio Sarriena s/n, 48940, Leioa, Spain.
Maite InsaustiDepartamento de Química Inorgánica, Facultad de Ciencia y Tecnología, UPV/EHU, Barrio Sarriena s/n, 48940, Leioa, Spain.
University of the Basque Country · ESBioCruces Health research Institute · ESIkerbasque · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Local heat generation from magnetic nanoparticles (MNPs) exposed to alternating magnetic fields can revolutionize cancer treatment. However, the application of MNPs as anticancer agents is limited by serious drawbacks. Foremost among these are the fast uptake and biodegradation of MNPs by cells and the unpredictable magnetic behavior of the MNPs when they accumulate within or around cells and tissues. In fact, several studies have reported that the heating power of MNPs is severely reduced in the cellular environment, probably due to a combination of increased viscosity and strong NP agglomeration. Herein, we present an optimized protocol to coat magnetite (Fe

Indexed as

AgarWaterCalorimetryCell Line, TumorEndocytosisHumansHyperthermia, InducedMagnetite NanoparticlesMagnetometryPolyethylene GlycolsAgarMagnetite NanoparticlesPolyethylene GlycolsWaterAC magnetometrycell-deathdipolar-interactionsendocytosismagnetic-hyperthermiamagnetite-nanoparticlesPEGylation

Identifiers

PMID32464047
PMCPMC8489799
OpenAlexW3032329009

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.