ArticleAngewandte Chemie (International ed. in English)2020
Trifluoromethyl Sulfoxides: Reagents for Metal-Free C-H Trifluoromethylthiolation.
Article in Angewandte Chemie (International ed. in English), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Recent Advances in C-H Perfluoroalkyl Thiolation and Perfluoroalkyl Sulfonylation.ACS organic & inorganic Au · 2025Review
- Immobilization of Palladium(II)acetate complex on dendrimer functionalized Cobalt ferrite nanoparticles as a nanocatalyst for Suzuki-Miyaura coupling and oxidation of sulfide.Scientific reports · 2025Article
- Impact of Fluorine Pattern on Lipophilicity and Acid-Base Properties of 2-(Thiofluoroalkyl)pyridines: Insights from Experiments and Statistical Modeling.Journal of medicinal chemistry · 2025Article
- Regioselective Substitution of BINOL.Chemical reviews · 2024Review
- Trifluoromethylthiolation of Arenes Using Lewis Acid and Lewis Base Dual Catalysis.The Journal of organic chemistry · 2024Article
- Regioselective C-H Thiocyanation of Arenes by Iron(III) Chloride Catalysis.The Journal of organic chemistry · 2023Article
- Synthesis of benzo[RSC advances · 2023Article
- Electrophilic Reagents for the Direct Incorporation of Uncommon SCFThe Journal of organic chemistry · 2022Article
- Generation of non-stabilized alkyl radicals from thianthrenium salts for C-B and C-C bond formation.Nature communications · 2021Article
- Straightforward Access to Thiocyanates via Dealkylative Cyanation of Sulfoxides.Organic letters · 2021Article
- Trifluoromethyl Sulfoxides: Reagents for Metal-Free C-H Trifluoromethylthiolation.Angewandte Chemie (International ed. in English) · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Trifluoromethyl sulfoxides are a new class of trifluoromethylthiolating reagent. The sulfoxides engage in metal-free C-H trifluoromethylthiolation with a range of (hetero)arenes. The method is also applicable to the functionalization of important compound classes, such as ligand derivatives and polyaromatics, and in the late-stage trifluoromethylthiolation of medicines and agrochemicals. The isolation and characterization of a sulfonium salt intermediate supports an interrupted Pummerer reaction mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.