ArticlePLoS biology2020
The haemodynamics of the human placenta in utero.
Article in PLoS biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 61 citations in OpenAlex.
- Placental Blood-Flow Velocity Quantification From Diffusion MRI.Magnetic resonance in medicine · 2026Article
- BRIDGING COTYLEDON PATHOLOGY AND PERFUSION IN HEALTHY PRIMATE PREGNANCY.bioRxiv : the preprint server for biology · 2026Article
- Recent innovations in placental MRI: Integrating visualization and functional imaging.Placenta · 2026Review
- Placental contractions in uncomplicated pregnancies.PloS one · 2026Observational
- The multifactorial role of HDAC9 at the maternal-fetal interface in the pathogenesis of preeclampsia.Clinical science (London, England : 1979) · 2025Review
- High-resolution MRI reveals uteroplacental flow dynamics in a 3D-printed human placental cotyledon model.Science advances · 2025Article
- Real-time fetal brain and placental T2* mapping at 0.55T MRI.Magnetic resonance in medicine · 2025Article
- The effects of maternal flow on placental diffusion-weighted MRI and intravoxel incoherent motion parameters.Magnetic resonance in medicine · 2025Article
- Placental quantitative susceptibility mapping and T2* characteristics for predicting birth weight in healthy and high-risk pregnancies.European radiology experimental · 2025Article
- Quantitative and longitudinal assessment of human placental inflammation using diffusion basis spectrum imaging.npj women's health · 2025Article
- Flow in fetoplacental-like microvessels in vitro enhances perfusion, barrier function, and matrix stability.Science advances · 2023Article
- B-Flow/Spatiotemporal Image Correlation M-Mode and Contrast-Enhanced/Microbubble Ultrasonography Quantification of Spiral Artery Distensibility and Placental Intervillous Perfusion in the First Trimester in a Primate Model of Impaired Spiral Artery Remodeling.Ultrasound in medicine & biology · 2023Article
- The human placenta project: Funded studies, imaging technologies, and future directions.Placenta · 2023Review
- Assessing within-subject rates of change of placental MRI diffusion metrics in normal pregnancy.Magnetic resonance in medicine · 2023Article
- Developments in functional imaging of the placenta.The British journal of radiology · 2023Review
- Low-Field Combined Diffusion-Relaxation MRI for Mapping Placenta Structure and Function.medRxiv : the preprint server for health sciences · 2023Article
- QSM Throughout the Body.Journal of magnetic resonance imaging : JMRI · 2023Review
- Feto-placental Unit: From Development to Function.Advances in experimental medicine and biology · 2023Review
- Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions.Scientific reports · 2022Article
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Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
We have used magnetic resonance imaging (MRI) to provide important new insights into the function of the human placenta in utero. We have measured slow net flow and high net oxygenation in the placenta in vivo, which are consistent with efficient delivery of oxygen from mother to fetus. Our experimental evidence substantiates previous hypotheses on the effects of spiral artery remodelling in utero and also indicates rapid venous drainage from the placenta, which is important because this outflow has been largely neglected in the past. Furthermore, beyond Braxton Hicks contractions, which involve the entire uterus, we have identified a new physiological phenomenon, the 'utero-placental pump', by which the placenta and underlying uterine wall contract independently of the rest of the uterus, expelling maternal blood from the intervillous space.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.