Evidence map›Paper›PMID 32463763›Full record

ArticleJCO oncology practice2020

Question Prompt List to Support Patient-Provider Communication in the Use of the 21-Gene Recurrence Test: Feasibility, Acceptability, and Outcomes.

Jinani Jayasekera, Susan T Vadaparampil, Susan Eggly, Richard L Street, Tanina Foster Moore, Claudine Isaacs, Hyo S Han, Bianca Augusto, Jennifer Garcia, Katherine Lopez and 1 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in JCO oncology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03183050 (MEND 2), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03183050 nacompletednot on this map

MEND 2: Making Treatment Decisions Using Genomic Testing

TypeinterventionalSponsorGeorgetown UniversityRan2017 to 2019Enrolled88ConditionsBreast Cancer FemaleArmsQuestion Prompt List
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Development of a Patient Question Prompt List for Older Adults with Early-Stage Hormone Receptor-Positive Breast Cancer.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Optimizing the design and implementation of question prompt lists to support person-centred care: A scoping review.Health expectations : an international journal of public participation in health care and health policy · 2023
    Article
  8. Article
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Jinani JayasekeraGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC.ORCID 0000-0001-9212-7225
Susan T VadaparampilMoffitt Cancer Center, Tampa, FL.
Susan EgglyKarmanos Cancer Center, Detroit, MI.
Richard L StreetTexas A&M University, College Station, TX.
Tanina Foster MooreKarmanos Cancer Center, Detroit, MI.ORCID 0000-0003-0232-348X
Claudine IsaacsGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC.ORCID 0000-0002-9646-1260
Hyo S HanMoffitt Cancer Center, Tampa, FL.
Bianca AugustoMoffitt Cancer Center, Tampa, FL.
Jennifer GarciaMoffitt Cancer Center, Tampa, FL.
Katherine LopezGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC.
Suzanne C O'NeillGeorgetown Lombardi Comprehensive Cancer Center, Washington, DC.ORCID 0000-0001-9942-6041
Georgetown Lombardi Comprehensive Cancer CenterMoffitt Cancer Center · USThe Barbara Ann Karmanos Cancer Institute · USTexas A&M University · US

Funding

A Question Prompt List to Promote Communication in Genomic MedicineR21CA201827 · NCI · GEORGETOWN UNIVERSITY · PI O'NEILL, SUZANNE C. · 2016 to 2017
$405k
A Simulation Model-based Framework to Support Oncology Guidelines and PracticeK99CA241397 · NCI · GEORGETOWN UNIVERSITY · PI JAYASEKERA, JINANI · 2020 to 2021
$351k
NCI NIH HHS K99 CA241397NCI NIH HHS R21 CA201827
6 · The paper itself

Abstract

purposeThe 21-gene recurrence score (RS) assay is used to guide breast cancer treatment decisions but can be poorly understood by patients. We examined the effects of a question prompt list (QPL) on knowledge, distress, and decisional conflict related to genomic testing and treatment in early-stage breast cancer.

methodsWe describe the feasibility and acceptability of the QPL and the impact of the QPL on knowledge, distress, and decisional conflict before and after the receipt of the QPL (MEND 2, N = 65). We also compared distress and decisional conflict between women who received the QPL (MEND 2, N = 65) and a comparable group of women who did not receive the QPL who participated in an earlier observational study within the same clinics (MEND 1, N = 136).

resultsMEND 2 participants indicated high acceptability and feasibility using the QPL. Knowledge increased post-QPL (

conclusionThe findings suggest that the QPL is feasible, acceptable, can improve knowledge and decrease decisional conflict in the large group of women deciding treatment while integrating RS test results.

Indexed as

CommunicationHealth Knowledge, Attitudes, PracticePhysician-Patient RelationsPsychological DistressBreast NeoplasmsDecision MakingFeasibility StudiesFemaleGenetic TestingHumansNeoplasm Recurrence, Local

Identifiers

PMID32463763
PMCPMC7564130
OpenAlexW3029394822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.