Evidence map›Paper›PMID 32463616›Full record

ArticleBiomedica : revista del Instituto Nacional de Salud2020

Comparison of Escherichia coli antibiotic-resistance profiles and incidence of betalactamase phenotypes in three private health facilities in Perú

Pool Marcos-Carbajal, Marco Galarza-Pérez, Salomón Huancahuire-Vega, Miguel Otiniano-Trujillo, Javier Soto-Pastrana

Abstract readComparative StudyMulticenter Study
In one paragraph

Article in Biomedica : revista del Instituto Nacional de Salud, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Phylogenetic Analysis ofInfection & chemotherapy · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pool Marcos-CarbajalLaboratorio de Microbiología, Escuela Profesional de Medicina Humana, Universidad Peruana Unión, Lima, Perú. poolmarcoscarbajal@gmail.com.
Marco Galarza-PérezLaboratorio de Microbiología, Escuela Profesional de Medicina Humana, Universidad Peruana Unión, Lima, Perú; Laboratorio de Referencia Nacional de Biotecnología y Biología Molecular, Instituto Nacional de Salud, Lima, Perú. marcogalarzaperez@gmail.com.
Salomón Huancahuire-VegaLaboratorio de Microbiología, Escuela Profesional de Medicina Humana, Universidad Peruana Unión, Lima, Perú. salomonhv7@gmail.com.
Miguel Otiniano-TrujilloLaboratorio de Microbiología, Escuela Profesional de Medicina Humana, Universidad Peruana Unión, Lima, Perú. mianoti@gmail.com.
Javier Soto-PastranaLaboratorio de Microbiología, Hospital Nacional Docente "Madre Niño San Bartolomé", Lima, Perú. orlansoto@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The appearance of multidrug-resistant and beta-lactamase producing enterobacteria in outpatient care facilities represent a public health problem in Perú. Objective: To compare the resistance profiles of uropathogenic Escherichia coli and to identify extended-spectrum beta-lactamase-producing phenotypes in three private health facilities located in the Peruvian coast, Andean and jungle regions. Materials and methods: We conducted a descriptive study on 98 urine samples from Lima (coast), Juliaca (Andean region) and Iquitos (jungle region) during 2016. We determined the antimicrobial susceptibility in 35 samples from Lima, 38 from Juliaca and 25 from Iquitos using eight antibiotic disks in samples from patients diagnosed with urinary infection. We also evaluated the production of extended-spectrum beta-lactamases with cefotaxime and ceftazidime disks and a combination of both with clavulanic acid on Mueller-Hinton agar. Results: We identified 18 resistance profiles ranging from those sensitive to others simultaneously resistant to seven antibiotics: 18.4% resistant to one and 54.0% to multiple antibiotics. We detected beta-lactamase production in 28.6% of the strains from the Puno region. Likewise, we observed a greater number of cases with resistance to ceftazidime, ceftriaxone, gentamicin, and trimethoprim-sulfamethoxazole in Puno’s health facility in patients within the 31 to 45 year age range. Conclusion: Resistance profiles varied according to the geographical location of the health facilities under study. Resistance to antibiotics was higher in the Andean region with 28.6% of strains producing extended-spectrum beta-lactamases.

Indexed as

AdolescentAdultAgedAged, 80 and overAnti-Bacterial Agentsbeta-LactamasesChildChild, PreschoolDrug Resistance, BacterialEscherichia coliHealth FacilitiesHumansInfantMiddle AgedPeruPhenotypeAnti-Bacterial Agentsbeta-Lactamasesbeta-lactamasesdisk diffusion antimicrobial testsdrug resistanceEnterobacteriaceaePerúurinary tract infections

Identifiers

PMID32463616
PMCPMC7449102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.