Evidence map›Paper›PMID 32463355›Full record

ArticleeLife2020

Genomic innovation of ATD alleviates mistranslation associated with multicellularity in Animalia.

Santosh Kumar Kuncha, Vinitha Lakshmi Venkadasamy, Gurumoorthy Amudhan, Priyanka Dahate, Sankara Rao Kola, Sambhavi Pottabathini, Shobha P Kruparani, P Chandra Shekar, Rajan Sankaranarayanan

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Mammalian Tolerance to Amino Acid Heterochirality.Chembiochem : a European journal of chemical biology · 2025
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Santosh Kumar KunchaCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0002-2538-8342
Vinitha Lakshmi VenkadasamyCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0001-7236-2615
Gurumoorthy AmudhanCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0002-6974-6703
Priyanka DahateCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Sankara Rao KolaCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Sambhavi PottabathiniCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0002-7749-3400
Shobha P KruparaniCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0002-8955-1647
P Chandra ShekarCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.
Rajan SankaranarayananCSIR-Centre for Cellular and Molecular Biology, Hyderabad, India.ORCID 0000-0003-4524-9953
Centre for Cellular and Molecular Biology · IN

Funding

Council of Scientific and Industrial Research Healthcare Theme projectDepartment of Biotechnology , Ministry of Science and Technology Centre of ExcellenceDepartment of Biotechnology, Ministry of Science and Technology Centre of ExcellenceDepartment of Science and Technology, Ministry of Science and Technology DST-INSPIREScience and Engineering Research Board J. C. Bose Fellowship
6 · The paper itself

Abstract

The emergence of multicellularity in Animalia is associated with increase in ROS and expansion of tRNA-isodecoders. tRNA expansion leads to misselection resulting in a critical error of L-Ala mischarged onto tRNA

Indexed as

Protein BiosynthesisAmino Acyl-tRNA SynthetasesAnimalsBiological EvolutionCell LineChoanoflagellataEukaryotaGenomeGenomicsHumansHydrolasesMiceOxidative StressRNA, TransferThreonineAmino Acyl-tRNA SynthetasesHydrolasesRNA, TransferThreonineAminoacyl-tRNA Synthetasebiochemistrycell biologychemical biologymulticellularitynoneproofreadingproteostasistranslationtRNA Isodecoder

Identifiers

PMID32463355
PMCPMC7302879
OpenAlexW3030971559

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.