Evidence map›Paper›PMID 32463021›Full record

ArticleIET nanobiotechnology2020

Studies on binding of single-stranded DNA with reduced graphene oxide-silver nanocomposites.

Xi Li, Linqing Yang, Yunfei Wang, Zhongyu Du, Xuyan Mao, Dezhi Sun, Jun Liu, Yu Zhou, Xiangyu Xu

Erratum issuedAbstract read
In one paragraph

Article in IET nanobiotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Corrigendum.IET nanobiotechnology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Xi LiDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510006, Guangdong Province, People's Republic of China.
Linqing YangProgram for Scientific Research Innovation Team in Precision Medicine of Gynecologic Oncology, Affiliated Hospital of Jining Medical University, Jining 272067, Shandong Province, People's Republic of China.
Yunfei WangProgram for Scientific Research Innovation Team in Precision Medicine of Gynecologic Oncology, Affiliated Hospital of Jining Medical University, Jining 272067, Shandong Province, People's Republic of China.
Zhongyu DuCollege of Basic Medical, Jining Medical University, Jining 272067, Shandong Province, People's Republic of China.
Xuyan MaoCollege of Basic Medical, Jining Medical University, Jining 272067, Shandong Province, People's Republic of China.
Dezhi SunCollege of Chemistry and Chemical Engineering, Liaocheng University, Liaocheng 252059, Shandong Province, People's Republic of China.
Jun LiuCollege of Basic Medical, Jining Medical University, Jining 272067, Shandong Province, People's Republic of China.
Yu ZhouSchool of Public Health, Jining Medical College, Jining 272067, Shandong Province, People's Republic of China.
Xiangyu XuCollege of Basic Medical, Jining Medical University, Jining 272067, Shandong Province, People's Republic of China. xuxiangyu1212@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The binding reaction of reduced graphene oxide-silver nanocomposites (rGO-AgNCs) with calf thymus single-stranded DNA (ssDNA) was studied by ultraviolet-visible absorption, fluorescence spectroscopy and circular dichroism (CD), using berberine hemisulphate (BR) dye as a fluorescence probe. The absorbance of ssDNA increases, but the fluorescence intensity is quenched with the addition of rGO-AgNCs. The binding of rGO-AgNCs with ssDNA was able to increase the quenching effects of BR and ssDNA, and induce the changes in CD spectra. All of the evidence indicated that there was a relatively strong interaction between ssDNA and rGO-AgNCs. The data obtained from fluorescence experiments revealed that the quenching process of ssDNA caused by rGO-AgNCs is primarily due to complex formation, i.e. static quenching. The increasing trend of the binding equilibrium constant (

Indexed as

DNA, Single-StrandedGraphiteSilverCircular DichroismDNANanocompositesSpectrometry, Fluorescencecalf thymus DNADNADNA, Single-Strandedgraphene oxideGraphiteSilver

Identifiers

PMID32463021
PMCPMC8676041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.