Evidence map›Paper›PMID 32462966›Full record

ArticleJournal of feline medicine and surgery2020

Appetite-stimulating effect of gabapentin vs mirtazapine in healthy cats post-ovariectomy.

Marco Fantinati, Julien Trnka, Amélia Signor, Séverine Dumond, Géraldine Jourdan, Patrick Verwaerde, Nathalie Priymenko

Open access · greenAbstract readClinical Trial, Veterinary
In one paragraph

Article in Journal of feline medicine and surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Gabapentin: Clinical Use and Pharmacokinetics in Dogs, Cats, and Horses.Animals : an open access journal from MDPI · 2023
    Review
  10. Article
  11. Article
  12. Article
  13. Drug-Dosing Adjustment in Dogs and Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marco FantinatiNutrition Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.ORCID 0000-0002-5297-1752
Julien TrnkaNutrition Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.
Amélia SignorNutrition Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.
Séverine DumondAnaesthesia Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.
Géraldine JourdanAnaesthesia Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.
Patrick VerwaerdeEmergency, Critical Care and Anaesthesia Department, National Veterinary School of Alfort (ENVA), Maisons-Alfort, France.
Nathalie PriymenkoNutrition Department, National Veterinary School of Toulouse (ENVT), Toulouse, France.
École Nationale Vétérinaire de Toulouse · FRÉcole Nationale Vétérinaire d'Alfort · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of the study was to evaluate the appetite-stimulating effect of gabapentin by comparing it with mirtazapine in healthy cats in the first 8 h after ovariectomy surgery.

methodsThis double-masked, placebo-controlled, prospective clinical trial included 60 healthy cats presented to the hospital for ovariectomy: 20 received gabapentin, 21 received mirtazapine and 19 received a placebo immediately before and 6 h after surgery. Food was offered at 2, 4, 6 and 8 h post-ovariectomy. After each meal, food intake was measured. Data were analysed using repeated-measure ANOVA and a linear mixed-model analysis. Post-hoc Tukey's honest significant difference test was performed for multiple comparisons.

resultsFood intake increased in both treatment groups vs placebo. No statistically significant difference was found between cats treated with gabapentin or mirtazapine. CONCLUSIONS AND RELEVANCE: Cats receiving gabapentin ate more than cats in the placebo group. Thirty percent of cats in the gabapentin group covered their resting energy requirements, while none of the cats in the placebo group did. Gabapentin and mirtazapine produced similar effects on food intake.

Indexed as

AnalgesicsAnimalsAnticonvulsantsAppetiteAppetite StimulantsCatsDouble-Blind MethodFemaleGabapentinMirtazapineOvariectomyProspective StudiesAnalgesicsAnticonvulsantsAppetite StimulantsGabapentinMirtazapineAppetiteappetite-stimulating drugfood intakegabapentinmirtazapinenutritionorexigenic effect

Identifiers

PMID32462966
PMCPMC10814375
OpenAlexW3029945470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.