Evidence map›Paper›PMID 32462945›Full record

ArticleCOPD2020

Chronic Obstructive Pulmonary Disease Prevalence and Associated Factors in a Setting of Well-Controlled HIV, A Cross-Sectional Study.

Alex Kayongo, Adaeze C Wosu, Tasmia Naz, Faith Nassali, Robert Kalyesubula, Bruce Kirenga, Robert A Wise, Trishul Siddharthan, William Checkley

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in COPD, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05223114 (Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05223114 completednot on this mapstarted 2022, after this paper: background citation

Airway Microbiome and Th17-mediated Inflammation in COPD Among HIV-infected Individuals in a Rural Ugandan Cohort

TypeobservationalSponsorMakerere UniversityRan2022 to 2023Enrolled160ConditionsCOPD, HIV Infections, Respiratory DiseaseArmsNot applicable (N/A)
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. HIV-associated lung disease.Nature reviews. Disease primers · 2023
    Review
  11. Review
  12. Article
  13. Journal of personalized medicine · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Chronic obstructive pulmonary disease in HIV.Expert review of respiratory medicine · 2021
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Alex KayongoCollege of Health Sciences, Makerere University, Kampala, Uganda.
Adaeze C WosuDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Tasmia NazDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Faith NassaliCollege of Health Sciences, Makerere University, Kampala, Uganda.
Robert KalyesubulaCollege of Health Sciences, Makerere University, Kampala, Uganda.
Bruce KirengaCollege of Health Sciences, Makerere University, Kampala, Uganda.
Robert A WiseDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Trishul SiddharthanDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
William CheckleyDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Johns Hopkins University · USMakerere University · UG

Funding

UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
Effectiveness of Low-dose Theophylline for the Management of Biomass-associated COPD in PeruK23HL146946 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI SIDDHARTHAN, TRISHUL · 2019 to 2023
$985k
Investigating the role of altered lung microbiome in fueling Th17 mediated airway inflammation in COPD among HIV-infected individualR21TW012354 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KAYONGO, ALEX · 2022 to 2023
$573k
FIC NIH HHS D43 TW009340FIC NIH HHS R21 TW012354FIC NIH HHS R25 TW009340NHLBI NIH HHS K23 HL146946
6 · The paper itself

Abstract

In Sub-Saharan Africa, COPD remains prevalent but its association with HIV is not well characterized especially in rural settings. We assessed for COPD prevalence, associated factors and lung function profile among HIV-infected individuals attending ART clinics in rural Nakaseke district of Uganda. We enrolled HIV-positive participants from four HIV treatment centers in rural Uganda. Participants underwent spirometry testing following standard guidelines. We defined COPD as a post-bronchodilator FEV

Indexed as

AdultAgedAged, 80 and overAnti-Retroviral AgentsCD4 Lymphocyte CountCross-Sectional StudiesFemaleForced Expiratory VolumeHIV InfectionsHumansLinear ModelsLogistic ModelsMaleMiddle AgedPrevalencePulmonary Disease, Chronic ObstructiveAnti-Retroviral AgentsAIDSCOPDHIVHIV-associated COPD

Identifiers

PMID32462945
PMCPMC8126339
OpenAlexW3031066450

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.