Evidence map›Paper›PMID 32462782›Full record

ArticleMolecular microbiology2020

Mutually constructive roles of Ail and LPS in Yersinia pestis serum survival.

Chandan Singh, Hwayoung Lee, Ye Tian, Sara Schesser Bartra, Suzanne Hower, Lynn M Fujimoto, Yong Yao, Sergey A Ivanov, Rima Z Shaikhutdinova, Andrey P Anisimov and 3 more

Open access · greenAbstract read
In one paragraph

Article in Molecular microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Yersinia pestis ΔApplied and environmental microbiology · 2023
    Article
  9. Article
  10. Review
  11. Deletion of Yersinia pestisJournal of bacteriology · 2021
    Article
  12. Lipopolysaccharide of theBiomolecules · 2021
    Review
  13. Article
  14. Article
  15. When the Going Gets Rough: The Significance ofFrontiers in microbiology · 2021
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Chandan SinghCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Hwayoung LeeDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, PA, USA.
Ye TianCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Sara Schesser BartraDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Suzanne HowerDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Lynn M FujimotoCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Yong YaoCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Sergey A IvanovState Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russian Federation.
Rima Z ShaikhutdinovaState Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russian Federation.
Andrey P AnisimovState Research Center for Applied Microbiology and Biotechnology, Obolensk, Moscow Region, Russian Federation.
Gregory V PlanoDepartment of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.
Wonpil ImDepartment of Biological Sciences, Chemistry, and Bioengineering, Lehigh University, Bethlehem, PA, USA.
Francesca M MarassiCancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.ORCID 0000-0003-2695-5844
Sanford Burnham Prebys Medical Discovery Institute · USState Research Center for Applied Microbiology and Biotechnology · RUUniversity of Miami · USLehigh University · US

Funding

Tumor Microenvironment and Cancer ImmunologyP30CA030199 · NCI · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI ELENA B PASQUALE · 1985 to 2026
$107.2M
Membrane Protein Effectors of Pathogen Interactions With HostR35GM118186 · NIGMS · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI Francesca M Marassi · 2016 to 2026
$8.5M
Role of Yersinia pestis Ail-host ligand interactions in plagueR01AI130009 · NIAID · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI PLANO, GREGORY V · 2017 to 2021
$2.2M
NCI NIH HHS P30 CA030199NIAID NIH HHS R01 AI130009NIGMS NIH HHS R35 GM118186
6 · The paper itself

Abstract

The outer membrane is a key virulence determinant of gram-negative bacteria. In Yersinia pestis, the deadly agent that causes plague, the protein Ail and lipopolysaccharide (LPS)

Indexed as

Amino Acid MotifsAnti-Bacterial AgentsBacterial Outer Membrane ProteinsDrug Resistance, BacterialHumansLipopolysaccharidesMicrobial Sensitivity TestsMolecular Dynamics SimulationMutationPlagueProtein BindingProtein ConformationVirulence FactorsYersinia pestisAil protein, Yersinia pestisAnti-Bacterial AgentsBacterial Outer Membrane ProteinsLipopolysaccharidesVirulence FactorsAillipopolysaccharideLPSMDnanodiscnuclear magnetic resonancestructureYersinia pestis

Identifiers

PMID32462782
PMCPMC7594906
OpenAlexW3029220123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.