Evidence map›Paper›PMID 32462762›Full record

ArticlePediatric pulmonology2020

The importance of anti-vaping vigilance-EVALI in seven adolescent pediatric patients in Northeast Ohio.

Aoife Corcoran, John C Carl, Fariba Rezaee

Abstract readCase Reports
In one paragraph

Article in Pediatric pulmonology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. The impact of electronic cigarettes on airway epithelial barrier integrity in preclinical mouse model.American journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  3. Review
  4. Electronic cigarette exposure disrupts airway epithelial barrier function and exacerbates viral infection.American journal of physiology. Lung cellular and molecular physiology · 2023
    Article
  5. Vaping-Associated Lung Injury: A Review.Medicina (Kaunas, Lithuania) · 2022
    Review
  6. Article
  7. A Comprehensive Review of Vaping Use in Pediatric Patients and Recent Changes in Regulatory Laws.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022
    Article
  8. Article
  9. Article
  10. Vaping-related lung injury.Virchows Archiv : an international journal of pathology · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aoife CorcoranDepartment of Pediatrics, Cleveland Clinic Children's, Cleveland, Ohio.
John C CarlCentre for Pediatric Pulmonary Medicine, Cleveland Clinic Children's, Cleveland, Ohio.
Fariba RezaeeCentre for Pediatric Pulmonary Medicine, Cleveland Clinic Children's, Cleveland, Ohio.ORCID 0000-0002-7625-3341

Funding

Mechanisms of Airway Epithelial Barrier Dysfunction by Respiratory Syncytial Virus and Environmental StimuliR01HL148057 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI REZAEE, FARIBA · 2019 to 2023
$2.2M
NHLBI NIH HHS R01 HL148057NHLBI NIH HHS R01-HL-148057 (FR)
6 · The paper itself

Abstract

As of 18 February 2020, the e-cigarette or vaping product use-associated lung injury (EVALI) epidemic has claimed the lives of 68 patients in the USA with the total number of reported cases standing at 2807 to date. We present the clinical and radiologic findings, course of illness, and treatment of EVALI in seven adolescent patients in Northeast Ohio. Five of our patients required supplemental oxygen with four requiring intensive care unit care for respiratory support during admission. Three patients were treated with systemic steroids while inpatient. Bilateral opacities were seen on radiographic imaging of all seven of our patients. All patients were discharged alive on room air. However, impaired diffusing capacity of the lungs for carbon monoxide (DLCO) with nonobstructive spirometry was seen in patients that were tested postdischarge. This suggests that although recovery from the acute illness process of EVALI is achieved, there may be long-term impact on lung function in these patients. We recommend close follow-up with a pediatric pulmonologist where spirometry and DLCO can be performed.

Indexed as

Electronic Nicotine Delivery SystemsAdolescentAdrenal Cortex HormonesCritical CareFemaleHospitalizationHumansLungLung InjuryMaleOhioOxygenSpirometryVapingAdrenal Cortex HormonesOxygenacute respiratory distress syndrome (ARDS)cannabidiol (CBD)Centers for Disease Control and Prevention (CDC)diffusing capacity of the lungs for carbon monoxide (DLCO)e-cigarette or vaping product use-associated lung injury (EVALI)lung injurynonnicotine substances such as tetrahydrocannabinol (THC)respiratory failurevaping

Identifiers

PMID32462762
PMCPMC7384027

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.