Evidence map›Paper›PMID 32462557›Full record

ArticleMagma (New York, N.Y.)2020

Effectiveness of fat suppression using a water-selective binomial-pulse excitation in chemical exchange saturation transfer (CEST) magnetic resonance imaging.

Yu Zhao, Zhongliang Zu, Zhichao Wang, Zhenzhi Liu, Bin Guo, Xu Yan, Daniel F Gochberg, Jianqi Li

Open access · greenAbstract read
In one paragraph

Article in Magma (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Yu ZhaoShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, China.
Zhongliang ZuVanderbilt University Institute of Imaging Science, Vanderbilt University, 1161 21st Ave. S, Medical Center North AAA-3112, Nashville, TN, 37232-2310, USA.
Zhichao WangShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, China.
Zhenzhi LiuMolecular Imaging Program at Stanford, Department of Radiology, Stanford University, Stanford, CA, USA.
Bin GuoImage Processing Center, School of Astronautics, Beihang University, Beijing, China.
Xu YanMR Scientific Marketing, Siemens Healthineers, Shanghai, China.
Daniel F GochbergVanderbilt University Institute of Imaging Science, Vanderbilt University, 1161 21st Ave. S, Medical Center North AAA-3112, Nashville, TN, 37232-2310, USA. daniel.gochberg@vanderbilt.edu.
Jianqi LiShanghai Key Laboratory of Magnetic Resonance, School of Physics and Electronic Science, East China Normal University, 3663 North Zhongshan Road, Shanghai, 200062, China. jqli@phy.ecnu.edu.cn.
East China Normal University · CNVanderbilt University Medical Center · USBeihang University · CNSiemens (China) · CNStanford University · US

Funding

CERT Imaging of CancerR01CA184693 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOCHBERG, DANIEL F · 2014 to 2018
$1.6M
CERT Imaging of MuscleR01EB017767 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GOCHBERG, DANIEL F · 2014 to 2017
$1.4M
Foundation for the National Institutes of Health R01CA184693Foundation for the National Institutes of Health R01EB017767National Natural Science Foundation of China 81271533NCI NIH HHS R01 CA184693NIBIB NIH HHS R01 EB017767Social Science Foundation of China 15ZDB016
6 · The paper itself

Abstract

purposeThe purpose of this study was to characterize the individual contribution of multiple fat peaks to the measured chemical exchange saturation transfer (CEST) signal when using water-selective binomial-pulse excitation and to determine the effects of multiple fat peaks in the presence of B

methodsThe excitation profiles of multiple binomial pulses were simulated. A CEST sequence with binomial-pulse excitation and modified point-resolved spectroscopy localization was then applied to the in vivo lumbar spinal vertebrae to determine the signal contributions of three distinct groups of lipid resonances. These confounding signal contributions were measured as a function of the irradiation frequency offset to determine the effect of the multi-peak nature of the fat signal on CEST imaging of exchange sites (at 1.0, 2.0 and 3.5 ppm) and robustness in the presence of B

resultsNumerical simulations and in vivo experiments showed that water excitation (WE) using a 1-3-3-1 (WE-4) pulse provided the broadest signal suppression, which provided partial robustness against B

conclusionIn WE-4-based CEST magnetic resonance imaging, B

Indexed as

Magnetic Resonance ImagingWaterArtifactsPhantoms, ImagingWaterB0 inhomogeneityBody imagingCESTLipid artifactWater excitation

Identifiers

PMID32462557
PMCPMC8592310
OpenAlexW3030029445

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.