Evidence map›Paper›PMID 32462462›Full record

ArticleHeart and vessels2020

Intra-abdominal pressure and its relationship with markers of congestion in patients admitted for acute decompensated heart failure.

J Rubio-Gracia, I Giménez-López, M Sánchez-Marteles, C Josa-Laorden, J I Pérez-Calvo

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In one paragraph

Article in Heart and vessels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

J Rubio-GraciaServicio de Medicina Interna, Hospital Clínico Universitario "Lozano Blesa", Avda. San Juan Bosco nº 15, 50009, Zaragoza, Spain. jorgerubiogracia@gmail.com.ORCID http://orcid.org/0000-0002-4769-7154
I Giménez-LópezInstituto de investigación Sanitaria de Aragón (IIS), Zaragoza, Spain.
M Sánchez-MartelesServicio de Medicina Interna, Hospital Clínico Universitario "Lozano Blesa", Avda. San Juan Bosco nº 15, 50009, Zaragoza, Spain.
C Josa-LaordenServicio de Medicina Interna, Hospital Clínico Universitario "Lozano Blesa", Avda. San Juan Bosco nº 15, 50009, Zaragoza, Spain.
J I Pérez-CalvoServicio de Medicina Interna, Hospital Clínico Universitario "Lozano Blesa", Avda. San Juan Bosco nº 15, 50009, Zaragoza, Spain.
Hospital Clínico Universitario Lozano Blesa · ESUniversidad de Zaragoza · ES

Funding

Sociedad Española de Medicina Interna (SEMI) 30,000€
6 · The paper itself

Abstract

Systemic congestion is one of the mechanisms involved in acute decompensated heart failure (ADHF). Increased intra-abdominal pressure (IAP), elicited by abdominal congestion, has been related to acute kidney injury and prognosis. Nonetheless, the link between diuretic response, surrogate markers of congestion and renal function remains poorly understood. We measured IAP in 43 patients from a non-interventional, exploratory, prospective, single center study carried out in patients admitted for ADHF. IAP was measured with a calibrated electronic manometer through a catheter inserted in the bladder. Normal IAP was defined as < 12 mmHg. At baseline, median IAP was 15 mmHg, with a reduction over the next 72 h to a median of 12 mmHg. A higher IAP at admission was associated with higher baseline blood urea (83 mg/dL [62-138] vs. 50 mg/dL [35-65]; p = 0.007) and creatinine (1.30 mg/dL vs. 0.95 mg/dL; p = 0.027), and with poorer diuretic response 72 h after admission, either measured by diuresis (14.4 mL/mg vs. 21.6 mL/mg; [p = 0.005]) or natriuresis (1.2 mEqNa/mg vs. 2.0 mEqNa/mg; [p = 0.008]). A higher incidence for 1-year all-cause mortality (45.0% vs. 16.7%; log-rank test = 0.041) was observed among those patients with IAP > 12 mmHg at 72 h. In patients with ADHF, higher IAP at admission is associated with poorer baseline renal function and impaired diuretic response. The persistence of IAP at 72 h above 12 mmHg associates to longer length of hospital stay and higher 1-year all-cause mortality.

Indexed as

DiuresisAbdomenAcute DiseaseAgedAged, 80 and overCardio-Renal SyndromeFemaleHeart FailureHospitalizationHumansHyperemiaKidneyMalePressurePrognosisProspective StudiesCardiorrenal interactionsHeart failureIntra-abdominal pressureRenal failure

Identifiers

PMID32462462
OpenAlexW3029581522

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.