Evidence map›Paper›PMID 32462277›Full record

Trial reportClinical oral investigations2021

Effect of calcium hydroxide mixed with lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial.

Hakan Arslan, Ezgi Doğanay Yıldız, Hüseyin Sinan Topçuoğlu, Ebru Tepecik, Gizem Taş

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Hakan ArslanDepartment of Endodontics, Faculty of Dentistry, Health Sciences University, İstanbul, Turkey.
Ezgi Doğanay YıldızDepartment of Endodontics, Faculty of Dentistry, Bursa Uludağ University, 16059, Bursa, Turkey. dtezgidoganay@gmail.com.ORCID http://orcid.org/0000-0003-4113-7794
Hüseyin Sinan TopçuoğluDepartment of Endodontics, Faculty of Dentistry, Erciyes University, Kayseri, Turkey.
Ebru TepecikPrivate Practice, Dental Clinic, İstanbul, Turkey.
Gizem TaşÇorlu Oral and Dental Health Hospital, Tekirdağ, Turkey.
Bursa Uludağ Üni̇versi̇tesi̇ · TRErciyes University · TRSağlık Bilimleri Üniversitesi · TRTurkish Society of Hematology · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of calcium hydroxide mixed with lidocaine HCl on postoperative spontaneous pain. MATERIALS AND

methodsSixty patients having irreversible pulpitis and symptomatic apical periodontitis with a preoperative spontaneous pain and percussion pain which was more than 50 on a visual analogue scale (100 mm VAS) were included in this study. After the preparation of the root canals, the patients were randomly distributed into two groups according to the calcium hydroxide vehicle, control group (mixed with saline) and calcium hydroxide mixed with lidocaine HCl (n = 30). Postoperative spontaneous pain scores were recorded by a VAS every day for a week. Data were analysed using one-way analysis of variance, chi-squared test and Mann-Whitney U tests (p = 0.05).

resultsThe calcium hydroxide mixed with lidocaine HCl group resulted in significantly less pain compared with the calcium hydroxide mixed with saline group during days 1 to 4 (p < 0.05). There were no significant differences between the groups in terms of postoperative percussion pain levels (p > 0.05).

conclusionWithin the limitations of this study, it can be concluded that the calcium hydroxide mixed with lidocaine HCl can be beneficial in reducing postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis. CLINICAL RELEVANCE: The calcium hydroxide mixed with lidocaine HCl can be beneficial in reducing postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis. CLINICAL REGISTRATION NUMBER: TCTR20181121003.

Indexed as

Periapical PeriodontitisPulpitisCalcium HydroxideDouble-Blind MethodHumansLidocainePostoperative PainProspective StudiesCalcium HydroxideLidocaineApical periodontitisCalcium hydroxideEndodonticsLidocainePostoperative pain

Identifiers

PMID32462277
OpenAlexW3031381323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.