ArticleInternational journal of cardiology. Heart & vasculature2020
Increased prevalence of left ventricular diastolic dysfunction in adults with repaired coarctation of aorta.
Article in International journal of cardiology. Heart & vasculature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 26 citations in OpenAlex.
- Anti-obesity medications in adults with congenital heart disease: a comprehensive review and expert clinical recommendations.European heart journal. Quality of care & clinical outcomes · 2026Review
- Prediction of hypertension and restenosis under guideline-directed management in aortic coarctation: development and validation of machine-learning models.EClinicalMedicine · 2026Article
- Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report.Clinical case reports · 2026Article
- Myocardial Deformation and Its Relation to Ventricular Shape, Preload, and Afterload in Fetuses with Suspected Coarctation of the Aorta.Pediatric cardiology · 2026Article
- Multimodality Imaging Approach in Diagnosis and Follow-Up of Aortic Coarctation in Adulthood.Journal of clinical medicine · 2026Review
- Improvement of left ventricular systolic function after surgical repair for adult aortic coarctation.Journal of cardiology cases · 2025Article
- Temporal changes in prevalence and severity of pulmonary hypertension, and relationship to outcomes in coarctation of aorta.International journal of cardiology. Heart & vasculature · 2025Article
- Incidence, Correlates, and Prognostic Implications of New-Onset Atrial Fibrillation in Adults With Repaired Coarctation of Aorta.CJC pediatric and congenital heart disease · 2024Article
- Sex Differences in Outcomes of Adults with Repaired Coarctation of Aorta and Concomitant Aortic Valve Disease.CJC open · 2024Article
- Article
- Sudden death in adults with repaired coarctation of the aorta: A case for sex-based risk factors.International journal of cardiology. Congenital heart disease · 2024Article
- Determinants and prognostic implications of left atrial reverse remodelling after coarctation of aorta repair in adults.European heart journal. Cardiovascular Imaging · 2024Article
- Aortic arch shape after arch repair predicts exercise capacity: a multicentre analysis.European heart journal open · 2024Article
- Right Ventricular Function and Right Ventricular-Vascular Coupling Assessment After Coarctation Repair in Adults.CJC pediatric and congenital heart disease · 2023Article
- Coarctation of the Aorta: Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2023Review
- Relationship between left atrial myopathy and atrial fibrillation in adults with coarctation of aorta.American heart journal plus : cardiology research and practice · 2023Article
- Prognostic Value of the HJACC. Advances · 2022Article
- Hypertension after coarctation repair-a systematic review.Translational pediatrics · 2022Review
- Cardiac Remodeling and Disease Progression in Patients With Repaired Coarctation of Aorta and Aortic Stenosis.Circulation. Cardiovascular imaging · 2021Article
- Right Heart Dysfunction in Adults With Coarctation of Aorta: Prevalence and Prognostic Implications.Circulation. Cardiovascular imaging · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLeft ventricular (LV) pressure overload and coronary artery disease are common in patients with coarctation of aorta (COA), and they are risk factors for LV diastolic dysfunction. Patients with COA may have aortic vasculopathy that can result in LV pressure overload even in the absence of hemodynamically significant COA. We therefore hypothesized that patients with mild COA (without hemodynamically significant COA) will have more LV diastolic dysfunction compared to controls.
methodsAdult patients with mild COA (Doppler peak velocity < 2.5 m/s) were matched 1:1 to patients without structural heart disease using propensity score method based on age, sex, body mass index, hypertension and blood pressure. The objective was to compare LV diastolic dysfunction (defined as E/e' > 2 standard deviations above age-specific normative values) between adults with repaired COA and controls.
resultsOf 204 COA and 204 control patients (age 35 ± 12 years), patients with COA had higher septal and lateral E/e' ratio (12 ± 4 vs 9 ± 4, p = 0.009) and (10 ± 3 vs 7 ± 3, p < 0.001), respectively. Compared to controls, the prevalence of LV diastolic dysfunction was higher in patients with COA for every age group: <40 years (63% vs 13%, p < 0.001); 41-60 years (87% vs 33%, p < 0.001); age > 60 years (82% vs 56%, p = 0.076). Left ventricular mass index (LVMI) was the strongest determinant of E/e' (β = 2.71 per 10 g/m
conclusionLV diastolic dysfunction was common in patients with COA, and the association with LVMI suggests that patients with COA may have ongoing LV pressure overload in the absence of hemodynamically significant re-coarctation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.