Evidence map›Paper›PMID 32462036›Full record

ArticleBioMed research international2020

Clinical and Genetic Analyses of 38 Chinese Patients with Peutz-Jeghers Syndrome.

Bo-Da Wu, Yong-Jun Wang, Liang-Liang Fan, Hui Huang, Peng Zhou, Mei Yang, Xiao-Liu Shi

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. [Current research status of Peutz-Jeghers syndrome in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Family with Peutz-Jeghers syndrome in Indonesia.JGH open : an open access journal of gastroenterology and hepatology · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bo-Da WuDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0003-2757-5202
Yong-Jun WangDepartment of Gastroenterology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0001-5876-1775
Liang-Liang FanDepartment of Cell Biology, School of Life Science, Central South University, Changsha, Hunan 410012, China.ORCID https://orcid.org/0000-0001-7431-1838
Hui HuangDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0002-4175-3979
Peng ZhouDepartment of Pathology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0001-8328-6320
Mei YangDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0001-9574-2282
Xiao-Liu ShiDepartment of Medical Genetics, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011, China.ORCID https://orcid.org/0000-0002-9759-2254
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeutz-Jeghers syndrome (PJS) is a rare autosomal dominant inherited disease caused by a germline mutation in the

aimsWe aimed to summarize the main clinical and genetic features of Chinese PJS patients and assessed the genotype-phenotype correlations.

methodsThirty-eight patients clinically diagnosed with Peutz-Jeghers syndrome were included in this study from 2016 to 2019. Combined direct sequencing and multiplex ligation-dependent probe amplification tests were used to detect germline heterogeneous

resultsAll 26 probands and 12 affected relatives had germline heterogeneous

conclusionThis study expanded the spectrum of

Indexed as

AdolescentAdultAMP-Activated Protein Kinase KinasesAsian PeopleChildChild, PreschoolChinaCohort StudiesFemaleGerm-Line MutationHumansMaleMiddle AgedPeutz-Jeghers SyndromeProtein Serine-Threonine KinasesYoung AdultAMP-Activated Protein Kinase KinasesProtein Serine-Threonine KinasesSTK11 protein, human

Identifiers

PMID32462036
PMCPMC7240661
OpenAlexW3024377117

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.