Evidence map›Paper›PMID 32461979›Full record

ArticleBioMed research international2020

Systematic Investigation of Polyurethane Biomaterial Surface Roughness on Human Immune Responses

Sören Segan, Meike Jakobi, Paree Khokhani, Sascha Klimosch, Florian Billing, Markus Schneider, Dagmar Martin, Ute Metzger, Antje Biesemeier, Xin Xiong and 11 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Experimental Design (2Polymers · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Dendritic cell biocompatibility of ether-based urethane films.Journal of applied toxicology : JAT · 2021
    Article
  11. The Impact of Biomaterial Cell Contact on the Immunopeptidome.Frontiers in bioengineering and biotechnology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Sören SeganNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Meike JakobiNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Paree KhokhaniNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Sascha KlimoschNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Florian BillingNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Markus SchneiderUniversity of Applied Sciences, Reutlingen, Alteburgstr. 150, 72762 Reutlingen, Germany.
Dagmar MartinNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Ute MetzgerNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Antje BiesemeierNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Xin XiongNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Ashutosh MukherjeeNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.ORCID https://orcid.org/0000-0002-8162-598X
Heiko SteuerNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Bettina-Maria KellerUniversity of Tübingen, Geschwister-Scholl-Platz, 72074 Tübingen, Germany.
Thomas JoosNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Manfred SchmolzHOT Screen GmbH, Aspenhaustraße 25, 72770 Reutlingen, Germany.
Ulrich RothbauerNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Hanna HartmannNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Claus BurkhardtNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Günter LorenzUniversity of Applied Sciences, Reutlingen, Alteburgstr. 150, 72762 Reutlingen, Germany.ORCID https://orcid.org/0000-0003-4862-7825
Nicole Schneiderhan-MarraNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.
Christopher ShippNMI, Natural and Medical Sciences Institute at the University of Tübingen, Markwiesenstr. 55, 72770 Reutlingen, Germany.ORCID https://orcid.org/0000-0001-9691-1076
Natural and Medical Sciences Institute · DEReutlingen University · DEUniversity of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been widely shown that biomaterial surface topography can modulate host immune response, but a fundamental understanding of how different topographies contribute to pro-inflammatory or anti-inflammatory responses is still lacking. To investigate the impact of surface topography on immune response, we undertook a systematic approach by analyzing immune response to eight grades of medical grade polyurethane of increasing surface roughness in three

Indexed as

ImmunityAnti-Inflammatory AgentsBiocompatible MaterialsCytokinesHLA-DR AntigensHumansLeukocytes, MononuclearMacrophagesMaleMicroscopy, ConfocalMicroscopy, Electron, ScanningMonocytesPolyurethanesSurface PropertiesTHP-1 CellsT-LymphocytesAnti-Inflammatory AgentsBiocompatible MaterialsCytokinesHLA-DR AntigensPolyurethanes

Identifiers

PMID32461979
PMCPMC7240656
OpenAlexW3023949074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.