Evidence map›Paper›PMID 32461978›Full record

ArticleBioMed research international2020

Nozomu Abe, Hiroaki Toyama, Yutaka Ejima, Kazutomo Saito, Tsutomu Tamada, Masanori Yamauchi, Itsuro Kazama

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Adrenaline Auto-Injectors for Preventing Fatal Anaphylaxis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2025
    Review
  2. Retracted:BioMed research international · 2024
    Article
  3. Article
  4. AlphaNeural regeneration research · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Catechin synergistically potentiates mast cell-stabilizing property of caffeine.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2021
    Article
  9. Strategies for Mast Cell Inhibition in Food Allergy.The Yale journal of biology and medicine · 2020
    Review
4 · The record

Corrections and comments

  • Retraction · 2024-03-20Computer-Aided Content or Computer-Generated Content · Concerns/Issues about Data · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · Unreliable Results and/or Conclusions ·
  • Retracted
5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nozomu AbeDepartment of Anesthesiology, Tohoku University Hospital, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Hiroaki ToyamaDepartment of Anesthesiology, Tohoku University Hospital, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Yutaka EjimaDepartment of Anesthesiology, Tohoku University Hospital, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Kazutomo SaitoDepartment of Anesthesiology, Tohoku University Hospital, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Tsutomu TamadaDepartment of Respiratory Medicine, Tohoku University Graduate School of Medicine, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Masanori YamauchiDepartment of Anesthesiology, Tohoku University Hospital, Seiryo-cho, Aoba-ku, Sendai, Miyagi, Japan.
Itsuro KazamaMiyagi University, School of Nursing, Gakuen, Taiwa-cho, Kurokawa-gun, Miyagi, Japan.ORCID https://orcid.org/0000-0001-8487-647X
Tohoku University Hospital · JPMiyagi University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdrenaline quickly inhibits the release of histamine from mast cells. Besides

methodsEmploying the whole-cell patch-clamp technique in rat peritoneal mast cells, we examined the effects of adrenaline on the degranulation of mast cells and the increase in the Cm during exocytosis. We also examined the degranulation of mast cells in the presence or absence of

resultsAdrenaline dose-dependently suppressed the GTP-

conclusionsThis study provided electrophysiological evidence for the first time that adrenaline dose-dependently inhibited the process of exocytosis, confirming its usefulness as a potent mast cell stabilizer. The pharmacological blockade of

Indexed as

AnimalsElectrophysiologyEpinephrineExocytosisHumansMaleMast CellsPrazosinRatsRats, WistarReceptors, Adrenergic, alpha-1Adra1b protein, ratEpinephrinePrazosinReceptors, Adrenergic, alpha-1

Identifiers

PMID32461978
PMCPMC7243011
OpenAlexW3024395500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.