Evidence map›Paper›PMID 32461962›Full record

ArticleBioMed research international2020

Sorafenib-Loaded Long-Circulating Nanoliposomes for Liver Cancer Therapy.

Haiwei Ye, Liping Zhou, Haili Jin, Yunhua Chen, Die Cheng, Ying Jiang

Abstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Emerging nanomedicine for liver diseases treatment.Journal of nanobiotechnology · 2025
    Review
  4. The Immune Microenvironment in Liver Cancer: From Analysis to Targeting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Review
  6. Sorafenib-Drug Delivery Strategies in Primary Liver Cancer.Journal of functional biomaterials · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haiwei YeChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.ORCID https://orcid.org/0000-0002-6641-0286
Liping ZhouChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.
Haili JinChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.
Yunhua ChenChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.
Die ChengChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.
Ying JiangChemical Pharmaceutical Research Institute, Taizhou Vocational & Technical College, Taizhou 318000, P. R., China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A type of sorafenib- (SOR-) loaded long-circulating nanoliposome was constructed, and the targeting performance and antitumor effects of the prepared liposome were evaluated in the present study. Polyethylene glycol- (PEG-) modified long-circulating nanoliposomes (LC-NPs) were designed and prepared using reverse evaporation, and the LC-NPs were used for delivering sorafenib (LC-PEG-SOR-NPs). Then, the anti-VEGFR antibody as a targeting moiety was chemically coupled with LC-PEG-SOR-NPs to form liver cancer-targeted nanoliposomes (anti-VEGFR-LC-PEG-SOR-NPs). The drug entrapment and loading efficiency were measured. And the cancer-targeting performance and therapeutic efficiency were evaluated both

Indexed as

AnimalsAntibodies, MonoclonalAntineoplastic AgentsHumansLiposomesLiverLiver NeoplasmsMaleMice, Inbred BALB CNanocapsulesPolyethylene GlycolsReceptors, Vascular Endothelial Growth FactorSorafenibAntibodies, MonoclonalAntineoplastic AgentsLiposomesNanocapsulesPolyethylene GlycolsReceptors, Vascular Endothelial Growth FactorSorafenib

Identifiers

PMID32461962
PMCPMC7229545

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.