Evidence map›Paper›PMID 32461854›Full record

ArticleCureus2020

Parental Refusal to Lumbar Puncture: Effects on Treatment, Hospital Stay and Leave Against Medical Advice.

Mushtaq Ahmed, Muzamil Ejaz, Saad Nasir, Salma Mainosh, Ashraf Jahangeer, Mahnoor Bhatty, Zobia Razi

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Mushtaq AhmedPediatrics, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.
Muzamil EjazPediatrics, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.
Saad NasirInternal Medicine, United Medical and Dental College, Creek General Hospital, Karachi, PAK.
Salma MainoshPediatrics, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.
Ashraf JahangeerEpidemiology, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, PAK.
Mahnoor BhattyPediatrics, Dow Medical College, Karachi, PAK.
Zobia RaziPediatrics, Dow Medical College, Karachi, PAK.
Civil Hospital Karachi · PKDow University of Health Sciences · PKKarachi Medical and Dental College · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Lumbar puncture (LP) is an effective method in the diagnosis and management of central nervous system infections. Refusal to LP is associated with severe consequences. This study aims to examine the impact of parental LP refusal on treatment, the length of hospital stay, and the frequency of patients leaving against medical advice (LAMA). Method A cross-sectional study was conducted at the pediatric department of Civil Hospital, Karachi, from June 2018 to November 2019. All hospitalized patients suspected to have a central nervous system disease, which requires LP, were enrolled. Patients were followed for the duration of antibiotic and antiviral therapy, length of hospital stay, and LAMA. Results A total of 220 patients participated in the study, with the median age of nine (2-47) months. There were 113 (51.1%) males. The median length of hospital stay was 10 (4-14) days. The comparison of parental LP refusal with the length of hospital stay showed a significant difference (p-value <0.001) in the number of days of treatment among patients who received vancomycin (p-value =0.008) and meropenem (p-value =0.012). A significant association of parental LP refusal was also observed with meningoencephalitis and meningitis as provisional diagnosis (p-value =0.006). In particular, LAMA and death were found significantly higher among parents who refused LP (p-value <0.001).  Conclusion LP refusal has a significant effect on the treatment, hospital stay, and disposition outcomes. A large number of parents who declined the procedure left against medical advice or suffered grave medical consequences. Parental education addressing their concerns and beliefs, while explaining the indications, and need for performing LP can help effectively overcome this issue.

Indexed as

cns infectionsleave against medical advicelumbar puncture refusalmeningitis

Identifiers

PMID32461854
PMCPMC7243628
OpenAlexW3017511365

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.