Evidence map›Paper›PMID 32461836›Full record

ArticlePeerJ2020

Depigmenting potential of lichen extracts evaluated by in vitro and in vivo tests.

Paola Malaspina, Erica Catellani, Bruno Burlando, Daniele Brignole, Laura Cornara, Miriam Bazzicalupo, Simona Candiani, Valentina Obino, Vincenzo De Feo, Lucia Caputo and 1 more

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. In Vitro Anti-Aging Properties of aMolecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. The GenusMolecules (Basel, Switzerland) · 2022
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Paola MalaspinaDepartment of Pharmacy, University of Genoa, Genoa, Italy.
Erica CatellaniDepartment of Pharmacy, University of Genoa, Genoa, Italy.
Bruno BurlandoDepartment of Pharmacy, University of Genoa, Genoa, Italy.
Daniele BrignoleDepartment of Pharmacy, University of Genoa, Genoa, Italy.
Laura CornaraDISTAV, University of Genoa, Genoa, Italy.
Miriam BazzicalupoDISTAV, University of Genoa, Genoa, Italy.
Simona CandianiDISTAV, University of Genoa, Genoa, Italy.
Valentina ObinoDISTAV, University of Genoa, Genoa, Italy.
Vincenzo De FeoDIFARMA, University of Salerno, Fisciano, Italy.
Lucia CaputoDIFARMA, University of Salerno, Fisciano, Italy.
Paolo GiordaniDepartment of Pharmacy, University of Genoa, Genoa, Italy.
University of Genoa · ITUniversity of Salerno · ITInstituto Biofisika · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanin is the main pigment of human skin, playing the primary role of protection from ultraviolet radiation. Alteration of the melanin production may lead to hyperpigmentation diseases, with both aesthetic and health consequences. Thus, suppressors of melanogenesis are considered useful tools for medical and cosmetic treatments. A great interest is focused on natural sources, aimed at finding safe and quantitatively available depigmenting substances. Lichens are thought to be possible sources of this kind of compounds, as the occurrence of many phenolic molecules suggests possible effects on phenolase enzymes involved in melanin synthesis, like tyrosinase. In this work, we used four lichen species,

Indexed as

Cetraria islandicaLetharia vulpinaLichen secondary metabolitesMelanogenesisTyrosinaseZebrafish

Identifiers

PMID32461836
PMCPMC7233272
OpenAlexW3025979953

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.