Evidence map›Paper›PMID 32461703›Full record

ArticleJournal of the mechanics and physics of solids2020

Mechanobiology predicts raft formations triggered by ligand-receptor activity across the cell membrane.

Angelo R Carotenuto, Laura Lunghi, Valentina Piccolo, Mahnoush Babaei, Kaushik Dayal, Nicola Pugno, Massimiliano Zingales, Luca Deseri, Massimiliano Fraldi

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the mechanics and physics of solids, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Competition between elasticity and adhesion in caterpillar locomotion.Journal of the Royal Society, Interface · 2025
    Article
  3. Review
  4. Targeting Lipid Rafts as a Strategy Against Coronavirus.Frontiers in cell and developmental biology · 2020
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Angelo R CarotenutoDepartment of Structures for Engineering and Architecture, University of Napoli "Federico II", Italy.
Laura LunghiSmiling International School, formerly at the Department of Life Sciences and Biotech., University of Ferrara, Italy.
Valentina PiccoloDepartment of Civil, Environmental and Mechanical Engineering, University of Trento, Italy.
Mahnoush BabaeiDepartment of Civil and Environmental Engineering, Department of Mechanical Engineering, Carnegie Mellon, USA.
Kaushik DayalDepartment of Civil and Environmental Engineering, Department of Mechanical Engineering, Carnegie Mellon, USA.
Nicola PugnoDepartment of Civil, Environmental and Mechanical Engineering, University of Trento, Italy.
Massimiliano ZingalesSchool of Engineering and Materials Science, Queen Mary University of London, Mile End Road, London E1 4NS UK.
Luca DeseriDepartment of Civil, Environmental and Mechanical Engineering, University of Trento, Italy.
Massimiliano FraldiDepartment of Structures for Engineering and Architecture, University of Napoli "Federico II", Italy.
Carnegie Mellon University · USQueen Mary University of London · GBUniversity of Ferrara · ITUniversity of Palermo · ITUniversity of Trento · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustering of ligand-binding receptors of different types on thickened isles of the cell membrane, namely lipid rafts, is an experimentally observed phenomenon. Although its influence on cell's response is deeply investigated, the role of the coupling between mechanical processes and multiphysics involving the active receptors and the surrounding lipid membrane during ligand-binding has not yet been understood. Specifically, the focus of this work is on

Indexed as

Cell membraneGPCRG-protein coupled receptorsLigand-receptorLipid raftsMechanobiologySARS-CoV-2Structured deformations

Identifiers

PMID32461703
PMCPMC7243794
OpenAlexW3027213996

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.