Evidence map›Paper›PMID 32461693›Full record

ArticleNature2020

Electromechanical coupling in the hyperpolarization-activated K

Michael David Clark, Gustavo F Contreras, Rong Shen, Eduardo Perozo

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
11.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 80 citations in OpenAlex.

  1. Review
  2. Voltage-sensing domains: structural and functional diversity.European biophysics journal : EBJ · 2026
    Review
  3. Article
  4. OsKAT1 is a short Shaker potassium channel involved in root-to-shoot potassium translocation and contributes to rice grain yield.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Structure reveals a regulation mechanism of plant outward-rectifying KProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. GORK KNature communications · 2025
    Article
  13. Article
  14. Voltage sensors.Molecular pharmacology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael David ClarkDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Gustavo F ContrerasDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Rong ShenDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA.
Eduardo PerozoDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL, USA. eperozo@uchicago.edu.
University of Chicago · US

Funding

MEDICAL SCIENTIST TRAININGT32GM007281 · NIGMS · UNIVERSITY OF CHICAGO · PI CLARK, MARCUS RAMSAY · 1985 to 2022
$32.1M
Synthetic Antigen Binder CoreU54GM087519 · NIGMS · UNIVERSITY OF CHICAGO · PI ZHOU, MING · 2010 to 2017
$31.9M
HIGH RESOLUTION STRUCTURAL DYNAMICS OF K CHANNELSR01GM057846 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PEROZO, EDUARDO A · 1998 to 2018
$7.4M
Breakthrough Molecular Dynamics Research via an Anton2 SupercomputerR01GM116961 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BLOOD, PHILIP D. · 2016 to 2023
$3.0M
Structural basis for transmembrane Mg2+ transportR01GM088406 · NIGMS · UNIVERSITY OF CHICAGO · PI PEROZO, EDUARDO A · 2009 to 2012
$1.3M
Structural and pharmacological dynamics of KCNQ2: A cryoEM and biophysics studyF30MH116647 · NIMH · UNIVERSITY OF CHICAGO · PI CLARK, MICHAEL DAVID · 2018 to 2020
$150k
NIGMS NIH HHS R01 GM057846NIGMS NIH HHS R01 GM088406NIGMS NIH HHS R01 GM116961NIGMS NIH HHS T32 GM007281NIGMS NIH HHS U54 GM087519NIMH NIH HHS F30 MH116647
6 · The paper itself

Abstract

Voltage-gated potassium (K

Indexed as

ArabidopsisCryoelectron MicroscopyIon Channel GatingAllosteric RegulationArabidopsis ProteinsBinding SitesLipidsModels, MolecularPotassium Channels, Inwardly RectifyingProtein ConformationArabidopsis ProteinsKAT1 protein, ArabidopsisLipidsPotassium Channels, Inwardly Rectifying

Identifiers

PMID32461693
PMCPMC7747229
OpenAlexW3028886274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.