Evidence map›Paper›PMID 32461687›Full record

ReviewNature reviews. Urology2020

Introducing PIONEER: a project to harness big data in prostate cancer research.

Muhammad Imran Omar, Monique J Roobol, Maria J Ribal, Thomas Abbott, Paul-Michael Agapow, Sonia Araujo, Alex Asiimwe, Charles Auffray, Irina Balaur, Katharina Beyer and 37 more

Erratum issuedOpen access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

47 authors at 20 institutions in 9 countries.

Muhammad Imran OmarAcademic Urology Unit, University of Aberdeen, Aberdeen, UK. m.i.omar@abdn.ac.uk.ORCID 0000-0002-1597-3126
Monique J RoobolErasmus MC, Rotterdam, Netherlands.ORCID 0000-0001-6967-1708
Maria J RibalGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Thomas AbbottAstellas, Leiden, The Netherlands.
Paul-Michael AgapowImperial College London, London, UK.ORCID 0000-0003-1126-1479
Sonia AraujoIQVIA, London, UK.
Alex AsiimweBayer AG, Berlin, Germany.ORCID 0000-0002-7633-0220
Charles AuffrayAssociation EISBM, Vourles, France.ORCID 0000-0003-2226-7411
Irina BalaurAssociation EISBM, Vourles, France.ORCID 0000-0002-3671-895X
Katharina BeyerTranslational Oncology and Urology Research, King's College London, London, UK.
Chiara BerniniEuropean Alliance for Personalised Medicine (EAPM), Brussels, Belgium.
Anders BjartellDepartment of Translational Medicine, Lund University, Lund, Sweden.
Alberto BrigantiDepartment of Urology and Division of Experimental Oncology, Urological Research Institute, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.
John-Edward Butler-RansohoffBayer AG, Berlin, Germany.
Riccardo CampiGuidelines Office, European Association of Urology, Arnhem, Netherlands.ORCID 0000-0001-5237-0888
Marinel CavelaarsThe Hyve, Utrecht, Netherlands.
Bertrand De MeulderAssociation EISBM, Vourles, France.
Zsuzsanna DevecseriSanofi, Chilly-Mazarin, France.ORCID 0000-0001-7648-3633
Marc Dietrich VossSanofi, Chilly-Mazarin, France.ORCID 0000-0001-8618-766X
Konstantinos DimitropoulosGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Susan Evans-AxelssonDepartment of Translational Medicine, Lund University, Lund, Sweden.ORCID 0000-0002-4240-0550
Billy FranksAstellas, Leiden, The Netherlands.
Louise FullwoodPinsent Masons, Leeds, UK.
Denis HorganEuropean Alliance for Personalised Medicine (EAPM), Brussels, Belgium.
Emma Jane SmithGuidelines Office, European Association of Urology, Arnhem, Netherlands.
Amit KiranAstellas, Leiden, The Netherlands.
Kati KivinummiTampere University (TAU), Tampere, Finland.ORCID 0000-0002-5788-835X
Mark LambrechtSAS, Tervuren, Belgium.
Doron LancetWeizmann Institute, Rehovot, Israel.
Peter LindgrenThe Swedish Institute for Health Economics (IHE), Stockholm, Sweden.ORCID 0000-0002-8238-8189
Sara MacLennanAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.ORCID 0000-0003-1405-6964
Steven MacLennanAcademic Urology Unit, University of Aberdeen, Aberdeen, UK.ORCID 0000-0002-2691-8421
Maria Manuela NogueiraAssociation EISBM, Vourles, France.ORCID 0000-0002-8353-1979
Fredrik MoenThe Swedish Institute for Health Economics (IHE), Stockholm, Sweden.ORCID 0000-0003-2428-4485
Maxim MoinatThe Hyve, Utrecht, Netherlands.
Kishore PapineniAstellas, Leiden, The Netherlands.
Christian ReichIQVIA, London, UK.
Kristin ReicheFraunhofer IZI, Leipzig, Germany.ORCID 0000-0002-4452-4872
Stijn RogiersSAS, Tervuren, Belgium.
Claudio SartiniBayer AG, Berlin, Germany.
Kees van BochoveThe Hyve, Utrecht, Netherlands.ORCID 0000-0002-8589-0609
Femke van Diggelenttopstart, Utrecht, Netherlands.ORCID 0000-0001-6211-0529
Mieke Van HemelrijckTranslational Oncology and Urology Research, King's College London, London, UK.
Hein Van PoppelGuidelines Office, European Association of Urology, Arnhem, Netherlands.ORCID 0000-0002-7458-8578
Jihong ZongBayer AG, Berlin, Germany.
James N'DowGuidelines Office, European Association of Urology, Arnhem, Netherlands.
PIONEER Consortium
European Association of Urology · NLBayer (Germany) · DEJanssen (Belgium) · BEAstellas Pharma (Netherlands) · NLEuropean Institute for Systems Biology and MedicineSanofi (France) · FROrion Corporation (Finland) · FISwedish Institute for Health Economics · SETampere University · FIThe Hyve (Netherlands) · NLErasmus MC · NLFraunhofer Institute for Cell Therapy and Immunology · DEUniversity of Aberdeen · GBImperial College London · GBIQVIA (United Kingdom) · GBKing's College London · GBLund University · SERadboud University Nijmegen · NLTechnische Universität Dresden · DEVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Programme (BD4BO), the overarching goal of PIONEER is to provide high-quality evidence on prostate cancer management by unlocking the potential of big data. The project has identified critical evidence gaps in prostate cancer care, via a detailed prioritization exercise including all key stakeholders. By standardizing and integrating existing high-quality and multidisciplinary data sources from patients with prostate cancer across different stages of the disease, the resulting big data will be assembled into a single innovative data platform for research. Based on a unique set of methodologies, PIONEER aims to advance the field of prostate cancer care with a particular focus on improving prostate-cancer-related outcomes, health system efficiency by streamlining patient management, and the quality of health and social care delivered to all men with prostate cancer and their families worldwide.

Indexed as

Big DataBiomedical ResearchProstatic NeoplasmsHumansMale

Identifiers

PMID32461687
OpenAlexW3018527648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.