Evidence map›Paper›PMID 32461641›Full record

ArticleNature2020

Olfactory sniffing signals consciousness in unresponsive patients with brain injuries.

Anat Arzi, Liron Rozenkrantz, Lior Gorodisky, Danit Rozenkrantz, Yael Holtzman, Aharon Ravia, Tristan A Bekinschtein, Tatyana Galperin, Ben-Zion Krimchansky, Gal Cohen and 4 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04798456 (A Multimodal Approach to Personalized Tracking of Evolving State-Of-Consciousness in Brain- Injured Patients), which is not on this map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04798456 unknown statusnot on this map

A Multimodal Approach to Personalized Tracking of Evolving State-Of-Consciousness in Brain- Injured Patients

TypeobservationalSponsorParis Brain Institute (ICM)Ran2020 to 2023Enrolled150ConditionsDisorders of Consciousness, Minimally Conscious State, Unresponsive Wakefulness Syndrome, CaregiversArmsComa scales, Imaging, electrophysiology, body signals, and brain stimulation, Questionnaires
3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Science advances · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Participatory Development of an International Information Brochure on the Multimodal Assessment of Disorders of Consciousness.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  13. Article
  14. Review
  15. Review
  16. Observational
  17. Review
  18. Article
  19. Disorders of Consciousness Rehabilitation: Ethical Dimensions and Epistemic Dilemmas.Physical medicine and rehabilitation clinics of North America · 2024
    Review
  20. Covert consciousness.NeuroRehabilitation · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Anat ArziDepartment of Psychology, University of Cambridge, Cambridge, UK. anat.arzi@gmail.com.
Liron RozenkrantzAzrieli Center for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel.
Lior GorodiskyAzrieli Center for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel.
Danit RozenkrantzLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Yael HoltzmanAzrieli Center for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel.
Aharon RaviaAzrieli Center for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel.ORCID http://orcid.org/0000-0003-2183-9254
Tristan A BekinschteinDepartment of Psychology, University of Cambridge, Cambridge, UK.
Tatyana GalperinLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Ben-Zion KrimchanskyLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Gal CohenLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Anna OksamitniLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Elena AidinoffLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Yaron SacherLoewenstein Hospital Rehabilitation Center, Raanana, Israel.
Noam SobelAzrieli Center for Human Brain Imaging and Research, Weizmann Institute of Science, Rehovot, Israel. noam.sobel@weizmann.ac.il.ORCID http://orcid.org/0000-0002-3232-9391
Loewenstein Hospital Rehabilitation Center · ILWeizmann Institute of Science · ILUniversity of Cambridge · GBTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

After severe brain injury, it can be difficult to determine the state of consciousness of a patient, to determine whether the patient is unresponsive or perhaps minimally conscious

Indexed as

AdultArousalBrain InjuriesConsciousnessDiagnostic ErrorsFemaleHumansMaleOdorantsOlfactory PerceptionPersistent Vegetative StatePrognosisRecovery of FunctionSensitivity and SpecificitySmellSurvival Analysis

Identifiers

PMID32461641
OpenAlexW3021537670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.