Evidence map›Paper›PMID 32461578›Full record

ArticleCell death & disease2020

Activation of adenosine A

Raquel Boia, Manuel Salinas-Navarro, Alejandro Gallego-Ortega, Caridad Galindo-Romero, Inês D Aires, Marta Agudo-Barriuso, António Francisco Ambrósio, Manuel Vidal-Sanz, Ana Raquel Santiago

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Lipid Trolling to Optimize AJournal of medicinal chemistry · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
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  9. Review
  10. Article
  11. Activation of Adenosine AInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Raquel BoiaUniversity of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-0479-3066
Manuel Salinas-NavarroInstituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.
Alejandro Gallego-OrtegaInstituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.
Caridad Galindo-RomeroInstituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.
Inês D AiresUniversity of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal.
Marta Agudo-BarriusoInstituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.ORCID http://orcid.org/0000-0002-8566-9277
António Francisco AmbrósioUniversity of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal.
Manuel Vidal-SanzInstituto Murciano de Investigación Biosanitaria-Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.
Ana Raquel SantiagoUniversity of Coimbra, Coimbra Institute for Clinical and Biomedical Research (iCBR), Faculty of Medicine, Coimbra, Portugal. asantiago@fmed.uc.pt.ORCID http://orcid.org/0000-0002-7541-7041
Instituto Murciano de Investigación Biosanitaria · ESAssociation for Innovation and Biomedical Research on Light and Image · PTUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glaucoma is a progressive chronic retinal degenerative disease and a leading cause of global irreversible blindness. This disease is characterized by optic nerve damage and retinal ganglion cell (RGC) death. The current treatments available target the lowering of intraocular pressure (IOP), the main risk factor for disease onset and development. However, in some patients, vision loss progresses despite successful IOP control, indicating that new and effective treatments are needed, such as those targeting the neuroprotection of RGCs. Adenosine A

Indexed as

NeuroprotectionAdenosineAdenosine A3 Receptor AgonistsAnimalsAxonal TransportCell DeathCell SurvivalFemaleOcular HypertensionOptic NerveRats, Sprague-DawleyReceptor, Adenosine A3Retinal DegenerationRetinal Ganglion CellsUp-Regulation2-chloro-N(6)-(3-iodobenzyl)adenosine-5'-N-methyluronamideAdenosineAdenosine A3 Receptor AgonistsReceptor, Adenosine A3

Identifiers

PMID32461578
PMCPMC7253479
OpenAlexW3031250121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.