Evidence map›Paper›PMID 32461482›Full record

ArticleIndian journal of ophthalmology2020

Intravitreal bevacizumab for iatrogenic choroidal neovascular membrane following vitreoretinal surgery for retinal detachment.

Ramya Appanraj, Hema Duraiswamy, Veerappan Saravanan, George Manayath, Narendran Venkatapathy

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. A case of iatrogenic CNV following macular surgery.American journal of ophthalmology case reports · 2025
    Article
  2. A case of choroidal neovascularization following multiple repairs of a rhegmatogenous retinal detachment.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ramya AppanrajDepartment of Retina and Vitreous, Aravind Eye Hospital, Avinashi Road, Coimbatore, Tamil Nadu, India.
Hema DuraiswamyDepartment of Retina and Vitreous, Aravind Eye Hospital, Avinashi Road, Coimbatore, Tamil Nadu, India.
Veerappan SaravananDepartment of Retina and Vitreous, Aravind Eye Hospital, Avinashi Road, Coimbatore, Tamil Nadu, India.
George ManayathDepartment of Retina and Vitreous, Aravind Eye Hospital, Avinashi Road, Coimbatore, Tamil Nadu, India.
Narendran VenkatapathyDepartment of Retina and Vitreous, Aravind Eye Hospital, Avinashi Road, Coimbatore, Tamil Nadu, India.
Aravind Eye Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the successful use of intravitreal bevacizumab in the iatrogenic choroidal neovascular membrane (CNVM) following vitreoretinal surgery. A 69-year-old male underwent vitrectomy surgery with silicone oil (SO) tamponade for rhegmatogenous retinal detachment. During fluid air exchange, there was an accidental retinal touch at an area in the papillomacular bundle with the silicone tip cannula. He had persistent subretinal bleed at the area 1 month after surgery. The optical coherence tomography (OCT) showed a subretinal elevated lesion and fluorescein angiography (FFA) showed an active CNVM. The patient was treated with intravitreal bevacizumab in the SO-filled eye. At 1-month postinjection, the OCT revealed reduction in the size of CNVM. The patient underwent SO removal with the second dose of intravitreal bevacizumab. CNVM regressed with no recurrence on follow-up at 1 year. Iatrogenic CNVM is a rare complication following successful vitreoretinal surgery. Prompt diagnosis and treatment with intravitreal bevacizumab may be required for a favorable outcome. Iatrogenic choroidal neovascular membrane (CNVM) is an uncommon condition usually associated with retinal laser or iatrogenic trauma during vitrectomy. Very few cases of iatrogenic CNVM have been reported in the literature, and the functional outcome has generally been poor in these reports despite treatment with laser photocoagulation, intravitreal bevacizumab, photodynamic therapy, and surgical removal of neovascular membranes. We report this case to highlight this rare complication following vitrectomy and its response to antivascular endothelial growth facor (VEGF) therapy.

Indexed as

Choroidal NeovascularizationRetinal DetachmentVitreoretinal SurgeryAgedAngiogenesis InhibitorsBevacizumabFluorescein AngiographyHumansIatrogenic DiseaseIntravitreal InjectionsMaleTomography, Optical CoherenceVascular Endothelial Growth Factor AVisual AcuityAngiogenesis InhibitorsBevacizumabVascular Endothelial Growth Factor AAvastinchoroidal neovascular membraneintravitreal anti-VEGF agentslasersilicone oilvitrectomized eye

Identifiers

PMID32461482
PMCPMC7508106
OpenAlexW3029305112

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.