Evidence map›Paper›PMID 32461310›Full record

ArticleJournal of virology2020

Herpes Simplex Virus 1 Strains 17

Tristan R Grams, Terri G Edwards, David C Bloom

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tristan R GramsDepartment of Molecular Genetics & Microbiology, University of Florida College of Medicine, Gainesville, Florida, USA.
Terri G EdwardsDepartment of Molecular Genetics & Microbiology, University of Florida College of Medicine, Gainesville, Florida, USA.
David C BloomDepartment of Molecular Genetics & Microbiology, University of Florida College of Medicine, Gainesville, Florida, USA dbloom@ufl.edu.
Florida College · USUniversity of Florida · US

Funding

Molecular Genetics of HSV ReactivationR01AI048633 · NIAID · UNIVERSITY OF FLORIDA · PI BLOOM, DAVID C. · 2001 to 2023
$7.2M
BASIC MICROBIOLOGY &INFECTIOUS DISEASEST32AI007110 · NIAID · UNIVERSITY OF FLORIDA · PI Stephanie M Karst · 1985 to 2026
$4.3M
NIAID NIH HHS R01 AI048633NIAID NIH HHS T32 AI007110
6 · The paper itself

Abstract

Herpes simplex virus 1 (HSV-1) establishes a lifelong latent infection in peripheral nerve ganglia. Periodically, the virus reactivates from this latent reservoir and is transported to the original site of infection. Strains of HSV-1 have been noted to vary greatly in their virulence and reactivation efficiencies in animal models. While HSV-1 strain 17

Indexed as

Models, BiologicalCell LineHerpes SimplexHerpesvirus 1, HumanHumansNeuronsVirus ActivationVirus Latencyherpes simplex viruslatencyneurotropismneurovirulencereactivation

Identifiers

PMID32461310
PMCPMC7375381
OpenAlexW3026431131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.