Evidence map›Paper›PMID 32460852›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2020

Cardiac T2 mapping: robustness and homogeneity of standardized in-line analysis.

Marco Wiesmueller, Wolfgang Wuest, Rafael Heiss, Christoph Treutlein, Michael Uder, Matthias Stefan May

Abstract readComparative Study
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Society for Cardiovascular Magnetic Resonance reference values ("normal values") in cardiovascular magnetic resonance: 2025 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  3. Article
  4. Article
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  7. Multi-site comparison of parametric T1 and T2 mapping: healthy travelling volunteers in the Berlin research network for cardiovascular magnetic resonance (BER-CMR).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  8. Developing a medical device-grade TJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  9. Imaging Methods: Magnetic Resonance Imaging.Circulation. Cardiovascular imaging · 2023
    Review
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  11. Review
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  15. Feasibility of cardiac-synchronized quantitative TPhysics and imaging in radiation oncology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marco WiesmuellerDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany. marco.wiesmueller@uk-erlangen.de.
Wolfgang WuestDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany.
Rafael HeissDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany.
Christoph TreutleinDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany.
Michael UderDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany.
Matthias Stefan MayDepartment of Radiology, University Hospital Erlangen, Maximiliansplatz 3, 91054, Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeInterpretation of T2 values remains difficult due to limited comparability across hardware and software systems and the lack of validated measurement recommendations for the number and orientation of mandatory slices. Our aims were to provide a standardized comparison of intra- and inter-individual T2 values in the short and long axes and to investigate inter-scanner reproducibility. METHOD AND MATERIALS: Ninety cardiovascular magnetic resonance (CMR) studies in 30 healthy subjects were performed with three identical 1.5 T CMR scanners (same hardware and software) using a balanced steady-state free precession (bSSFP) gradient echo sequence in three short axis (SAx) and three long axis (LAx) views. A commercially available T2 mapping software package of the latest generation with automatic in-line motion correction was used for acquisition. Regions of interest were manually drawn in each of the 16 myocardial segments according to the American Heart Association (AHA) model in three SAx and three LAx acquisitions. Analysis of inter-scanner, inter-segmental, intra-segmental, inter-regional and inter-level differences was performed.

resultsInter-scanner reproducibility was high and the mean myocardial T2 value for all evaluated segments was 45.7 ± 3.4 ms. Significant inter-segmental variations of mean T2 values were found. Mean intra-segmental T2 values were comparable between LAx and SAx acquisitions in 72%. Significantly higher T2 values were found in apical segments and a significant disparity among different regions was found for SAx and LAx orientations.

conclusionStandardized cardiac T2 mapping is highly reproducible on identical CMR systems. T2 values vary significantly between single heart segments, regions, levels, and axes in young, healthy subjects.

Indexed as

Image Interpretation, Computer-AssistedSoftwareAdultFemaleHealthy VolunteersHeartHumansMagnetic Resonance Imaging, CineMaleObserver VariationPredictive Value of TestsProspective StudiesReproducibility of ResultsYoung AdultCardiovascular imaging, cardiovascular magnetic resonanceMRIT2 mapping

Identifiers

PMID32460852
PMCPMC7254724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.