Evidence map›Paper›PMID 32460808›Full record

ArticleBMC research notes2020

Aescin and diosmin each alone or in low dose- combination ameliorate liver damage induced by carbon tetrachloride in rats.

Sara Mahmmoud El-Dakhly, Abeer Abdallah Ali Salama, Soha Osama Mahmoud Hassanin, Noha Nazeeh Yassen, Alaaeldin Ahmed Hamza, Amr Amin

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 88 citations in OpenAlex.

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  14. Determination of Therapeutic and Safety Effects ofBioMed research international · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Pharmacology of Diosmin, a Citrus Flavone Glycoside: An Updated Review.European journal of drug metabolism and pharmacokinetics · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Sara Mahmmoud El-DakhlyFaculty of Pharmacy, Modern University for Technology and Information, Cairo, Egypt.
Abeer Abdallah Ali SalamaPharmacology Department, National Research Centre, Giza, Egypt.ORCID http://orcid.org/0000-0001-9870-5583
Soha Osama Mahmoud HassaninBiochemistry Department, Modern University for Technology and Information, Cairo, Egypt.ORCID http://orcid.org/0000-0001-8568-1033
Noha Nazeeh YassenPathology Department, National Research Centre, Giza, Egypt.ORCID http://orcid.org/0000-0001-7641-2886
Alaaeldin Ahmed HamzaHormone Evaluation Department, National Organization for Drug Control and Research, Giza, Egypt.
Amr AminBiology Department, UAE University, Al Ain, UAE. a.amin@uaeu.ac.ae.ORCID http://orcid.org/0000-0001-8888-1102
Modern University for Information and Technology · EGNational Research Centre · EGAl Ain University · AENational Organization for Drug Control and Research · EG

Funding

Al Jalila Foundation 21S098
6 · The paper itself

Abstract

objectiveThis study evaluated hepatoprotective effect of aescin (AES) and diosmin (DIO), individually or in low-dose combination in chemically induced liver injury in rats. Rats were divided into 6 groups; Group 1, control, Group 2, injected with a single dose of a mixture of corn oil and carbon tetrachloride (CCl

resultsResults indicated that CCl

Indexed as

AnimalsCarbon TetrachlorideChemical and Drug Induced Liver InjuryDiosminDrug CombinationsEscinMaleProtective AgentsRatsRats, WistarSilymarinCarbon TetrachlorideDiosminDrug CombinationsEscinProtective AgentsSilymarinAescinCarbon tetrachlorideDiosminLiverRats

Identifiers

PMID32460808
PMCPMC7251915
OpenAlexW3031160314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.