Evidence map›Paper›PMID 32460801›Full record

Trial reportJournal of the International Society of Sports Nutrition2020

The addition of β-Hydroxy β-Methylbutyrate (HMB) to creatine monohydrate supplementation does not improve anthropometric and performance maintenance across a collegiate rugby season.

Gerald T Mangine, Trisha A VanDusseldorp, Garrett M Hester, Jennifer M Julian, Yuri Feito

Open access · goldAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of the International Society of Sports Nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Frontiers in nutrition · 2025
    Pooled it
  2. Trial
  3. International society of sports nutrition position stand: β-hydroxy-β-methylbutyrate (HMB).Journal of the International Society of Sports Nutrition · 2025
    Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gerald T MangineExercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, 30144, Kennesaw, GA, Georgia. gmangine@kennesaw.edu.ORCID http://orcid.org/0000-0003-2718-2564
Trisha A VanDusseldorpExercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, 30144, Kennesaw, GA, Georgia.
Garrett M HesterExercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, 30144, Kennesaw, GA, Georgia.
Jennifer M JulianExercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, 30144, Kennesaw, GA, Georgia.
Yuri FeitoExercise Science and Sport Management, Kennesaw State University, 520 Parliament Garden Way NW, 30144, Kennesaw, GA, Georgia.
Kennesaw State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMuscular damage sustained while playing rugby may hinder performance across a season. β-Hydroxy β-Methylbutyrate (HMB) may help attenuate muscle damage and maintain lean mass and performance. This study sought to determine the effect of combining HMB with creatine monohydrate supplementation on measures of stress and muscle damage, body composition, strength and sprinting kinetics throughout a rugby season.

methodsThis double-blind, cross-over investigation recruited 16 male collegiate rugby players to provide resting blood samples and complete assessments of body composition, strength and sprinting performance prior to their fall season (PRE

resultsLinear mixed models with repeated measures revealed group x time interactions (p <  0.05) for observed for several measures but did not consistently and positively favor one group. During the fall season, knee extensor peak torque was reduced by 40.7 ± 28.1 Nm (p = 0.035) for HMB-Cr but remained consistent for Cr, and no group differences or changes were noted in the spring. In the spring, greater knee flexor rate of torque development (~ 149 Nm·sec

conclusionsThe combination of HMB and creatine monohydrate supplementation does not provide a greater ergogenic benefit compared to creatine monohydrate supplementation alone. Body composition, strength, and sprinting ability did not change across the season with creatine monohydrate supplementation.

Indexed as

Body CompositionDietary SupplementsFootballAthletic PerformanceCreatineCreatine KinaseCross-Over StudiesDouble-Blind MethodHumansHydrocortisoneMaleSports Nutritional Physiological PhenomenaValeratesYoung Adultbeta-hydroxyisovaleric acidCreatineCreatine KinaseHydrocortisoneValeratesAthletesCortisolCreatine kinaseSprinting kineticsStrength

Identifiers

PMID32460801
PMCPMC7254750
OpenAlexW3029418386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.