Evidence map›Paper›PMID 32460474›Full record

ReviewJournal of pathology and translational medicine2020

Current status and future perspectives of liquid biopsy in non-small cell lung cancer.

Sunhee Chang, Jae Young Hur, Yoon-La Choi, Chang Hun Lee, Wan Seop Kim

Open access · goldAbstract readReview
In one paragraph

Review in Journal of pathology and translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Update on molecular pathology and role of liquid biopsy in nonsmall cell lung cancer.European respiratory review : an official journal of the European Respiratory Society · 2021
    Review
  11. Real-World Analysis of theDiagnostics (Basel, Switzerland) · 2021
    Article
  12. Review
  13. Article
  14. Future Perspectives in DetectingInternational journal of molecular sciences · 2021
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Sunhee ChangDepartment of Pathology, Inje University Ilsan Paik Hospital, Goyang, Korea.
Jae Young HurDepartment of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
Yoon-La ChoiDepartment of Pathology and Translational Genomics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chang Hun LeeDepartment of Pathology, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Wan Seop KimDepartment of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea.
Konkuk University Medical Center · KRInje University Ilsan Paik Hospital · KRPusan National University Hospital · KRSamsung Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With advances in target therapy, molecular analysis of tumors is routinely required for treatment decisions in patients with advanced non-small cell lung cancer (NSCLC). Liquid biopsy refers to the sampling and analysis of circulating cell-free tumor DNA (ctDNA) in various body fluids, primarily blood. Because the technique is minimally invasive, liquid biopsies are the future in cancer management. Epidermal growth factor receptor (EGFR) ctDNA tests have been performed in routine clinical practice in advanced NSCLC patients to guide tyrosine kinase inhibitor treatment. In the near future, liquid biopsy will be a crucial prognostic, predictive, and diagnostic method in NSCLC. Here we present the current status and future perspectives of liquid biopsy in NSCLC.

Indexed as

BiomarkersCarcinoma, non-small cell lung cancerCirculating tumor DNAEpidermal growth factor receptorLiquid biopsy

Identifiers

PMID32460474
PMCPMC7253954
OpenAlexW3016930818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.