Evidence map›Paper›PMID 32460358›Full record

ReviewImmunology2020

The early landscape of coronavirus disease 2019 vaccine development in the UK and rest of the world.

Hannah R Sharpe, Ciaran Gilbride, Elizabeth Allen, Sandra Belij-Rammerstorfer, Cameron Bissett, Katie Ewer, Teresa Lambe

Open access · hybridAbstract readReview
In one paragraph

Review in Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
2.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
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  6. Review
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  15. Article
  16. Article
  17. Current trends in diagnosis and treatment strategies of COVID-19 infection.Environmental science and pollution research international · 2021
    Review
  18. Article
  19. Article
  20. Understanding Drivers of Coronavirus Disease 2019 Vaccine Hesitancy Among Blacks.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hannah R SharpeThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-1194-2429
Ciaran GilbrideThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-6883-666X
Elizabeth AllenThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-6406-4834
Sandra Belij-RammerstorferThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0002-8637-3785
Cameron BissettThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-3345-663X
Katie EwerThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0001-9827-9836
Teresa LambeThe Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0001-7711-897X
University of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the first World Health Organization notification on 31 December 2019, coronavirus disease 2019 (COVID-19), the respiratory disease caused by the coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has been responsible for over four million confirmed infections and almost 300 000 deaths worldwide. The pandemic has led to over half of the world's population living under lockdown conditions. To allow normal life to resume, public health interventions will be needed to prevent further waves of infections as lockdown measures are lifted. As one of the most effective countermeasures against infectious diseases, an efficacious vaccine is considered crucial to containing the COVID-19 pandemic. Following the publication of the genome sequence of SARS-CoV-2, vaccine development has accelerated at an unprecedented pace across the world. Here we review the different platforms employed to develop vaccines, the standard timelines of development and how they can be condensed in a pandemic situation. We focus on vaccine development in the UK and vaccines that have entered clinical trials around the world.

Indexed as

Viral VaccinesAnimalsClinical Trials as TopicCoronavirus InfectionsCOVID-19COVID-19 VaccinesHumansPandemicsPneumonia, ViralProtein SubunitsUnited KingdomVaccines, AttenuatedVaccines, DNAVaccines, SyntheticCOVID-19 VaccinesProtein SubunitsVaccines, AttenuatedVaccines, DNAVaccines, SyntheticViral Vaccinescoronavirus disease 2019severe acute respiratory syndrome coronavirus-2vaccine

Identifiers

PMID32460358
PMCPMC7283842
OpenAlexW3030351136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.