Evidence map›Paper›PMID 32459982›Full record

Observational studyGut microbes2020

Metagenomics reveals impact of geography and acute diarrheal disease on the Central Indian human gut microbiome.

Tanya M Monaghan, Tim J Sloan, Stephen R Stockdale, Adam M Blanchard, Richard D Emes, Mark Wilcox, Rima Biswas, Rupam Nashine, Sonali Manke, Jinal Gandhi and 7 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 3 countries.

Tanya M MonaghanNIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham , Nottingham, UK.
Tim J SloanSchool of Life Sciences, University of Nottingham , Nottingham, UK.ORCID 0000-0003-3668-7775
Stephen R StockdaleAPC Microbiome Ireland, University College Cork , Cork, Ireland.ORCID 0000-0002-0044-3878
Adam M BlanchardSchool of Veterinary Medicine and Science, Sutton Bonington Campus, University of Nottingham , Leicestershire, UK.ORCID 0000-0001-6991-7210
Richard D EmesSchool of Veterinary Medicine and Science, Sutton Bonington Campus, University of Nottingham , Leicestershire, UK.ORCID 0000-0001-6855-5481
Mark WilcoxLeeds Teaching Hospitals NHS Trust and University of Leeds , UK.ORCID 0000-0002-4565-2868
Rima BiswasBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Rupam NashineBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Sonali MankeBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Jinal GandhiBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Pratishtha JainBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Shrejal BhotmangeBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Shrikant AmbalkarDepartment of Clinical Microbiology and Infection, King's Mill Hospital, Sherwood Forest Hospitals NHS Trust , Sutton in Ashfield, UK.
Ashish SatavMahatma Gandhi Tribal Hospital , Dharni, India.
Lorraine A DraperAPC Microbiome Ireland, University College Cork , Cork, Ireland.
Colin HillAPC Microbiome Ireland, University College Cork , Cork, Ireland.ORCID 0000-0002-8527-1445
Rajpal Singh KashyapBiochemistry Research Centre, Central India Institute of Medical Sciences , Nagpur, India.
Central India Institute of Medical Sciences · INUniversity College Cork · IEUniversity of Nottingham · GBNottingham University Hospitals NHS Trust · GBSherwood Forest Hospitals NHS Foundation Trust · GBUniversity of Leeds · GB

Funding

Department of Health
6 · The paper itself

Abstract

backgroundThe Central Indian gut microbiome remains grossly understudied. Herein, we sought to investigate the burden of antimicrobial resistance and diarrheal diseases, particularly

resultsWe observed distinct rural-urban differences in bacterial and viral populations, with geography exhibiting a greater influence than diarrheal status.

conclusionsWe report distinct differences in antimicrobial resistance gene profiles, enrichment of metabolic pathways and phage composition between rural and urban populations, as well as a higher burden of

Indexed as

AdultAgedAnti-Bacterial AgentsBacteriaCarbapenemsCephalosporinsClostridioides difficileDiarrheaEnterocolitis, PseudomembranousFemaleGastrointestinal MicrobiomeHumansIndiaMaleMetagenomicsMiddle AgedAnti-Bacterial AgentsCarbapenemsCephalosporinsantibiotic resistomeCentral IndiaClostridioides difficilediarrheaGut microbiomevirome

Identifiers

PMID32459982
PMCPMC7781581
OpenAlexW3019255739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.