Evidence map›Paper›PMID 32459852›Full record

ArticleAnnals of work exposures and health2020

Allergic and Respiratory Symptoms in Employees of Indoor Cannabis Grow Facilities.

Coralynn Sack, Niloufar Ghodsian, Karen Jansen, Brynne Silvey, Christopher D Simpson

Open access · bronzeAbstract read
In one paragraph

Article in Annals of work exposures and health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Should cannabis self-cultivation be part of a public health‒oriented legalization policy framework?Canadian journal of public health = Revue canadienne de sante publique · 2024
    Article
  4. Review
  5. Review
  6. Stress, Mental Health, and Coping Among Workers in the Northern California Cannabis Industry: A Qualitative Descriptive Analysis.New solutions : a journal of environmental and occupational health policy : NS · 2024
    Article
  7. Fatal Occupational Asthma in Cannabis Production - Massachusetts, 2022.MMWR. Morbidity and mortality weekly report · 2023
    Article
  8. Article
  9. Article
  10. The Emerging Spectrum of Respiratory Diseases in the U.S. Cannabis Industry.Seminars in respiratory and critical care medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Coralynn SackDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Niloufar GhodsianDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Karen JansenDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Brynne SilveyDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
Christopher D SimpsonDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, WA, USA.
University of Washington · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Joel Daniel Kaufman · 1995 to 2026
$42.5M
University of Washington Education and Research CenterT42OH008433 · OH · UNIVERSITY OF WASHINGTON · PI SIMPSON, CHRISTOPHER D · 2005 to 2024
$29.4M
Pacific Northwest Agricultural Safety and Health Center-RenewalU54OH007544 · OH · UNIVERSITY OF WASHINGTON · PI YOST, MICHAEL G · 2011 to 2025
$23.0M
The Role of Airway Morphology in Environmental LungDiseasesK23ES030725 · NIEHS · UNIVERSITY OF WASHINGTON · PI SACK, CORALYNN SHAYNA · 2019 to 2023
$835k
NIEHS NIH HHS K23 ES030725NIEHS NIH HHS P30 ES007033NIOSH CDC HHS T42 OH008433NIOSH CDC HHS U54 OH007544
6 · The paper itself

Abstract

backgroundWhile little is known about the occupational hazards associated with Cannabis cultivation, both historical research in the hemp industry and preliminary data from modern grow houses, suggest that Cannabis workers may be at increased risk of respiratory and allergic diseases.

objectivesWe sought to investigate the association between workplace exposures and health symptoms in an indoor Cannabis grow facility in Washington State, USA.

methodsWe performed a cross-sectional study with all consenting employees in an indoor Cannabis grow facility in Seattle, WA using a questionnaire. The questionnaire gathered data on respiratory, ocular, nasal, and dermal symptoms. A subset of employees with work-related symptoms underwent repeated cross-shift and cross-week measurement of spirometry, fractional exhaled nitrogen oxide (FeNO), and skin prick testing for Cannabis sensitization. Exposure to Cannabis dust was classified based on self-described tasks, expert opinion, and exposure monitoring of particulate matter. Multivariable logistic regression was undertaken to examine associations between exposure to Cannabis dust (classified as low, medium, and high) and health symptoms. Linear mixed effects models examined the relationship between cross-shift and cross-week changes in spirometry and FeNO.

resultsNinety-seven percent (97%) of the employees (n = 31) surveyed were recreational cannabis users, with 81% (n = 25) smoking cannabis multiple times per day. Twenty-two (71%) employees reported one or more work-related symptoms: 65% respiratory, 39% ocular, 32% nasal, and 26% dermal symptoms. There was a trend toward increased likelihood of work-related symptoms with increasing exposure to Cannabis dust, although none of these results were statistically significant. Of the 10 employees with work-aggravated symptoms, 5 had borderline-high or high FeNO, 7 had abnormal spirometry, and 5 had evidence of Cannabis sensitization on skin prick testing. FeNO increased by 3.78 ppb (95% confidence interval 0.68-6.88 ppb) across the work-week and there was a trend toward cross-week and cross-shift reduced airflow.

conclusionsWe found a high prevalence of work-related allergic- and particularly respiratory symptoms in the employees of one indoor Cannabis grow facility in Washington State. A high proportion of employees with work-aggravated symptoms had findings consistent with probable work-related asthma based on high FeNO, airflow obstruction on spirometry, and Cannabis sensitization on skin prick testing. However, due to the high incidence of recreational cannabis use among these workers, the relative influence of occupational versus recreational exposure to Cannabis dust on the respiratory health and sensitization status of these workers could not be resolved in this study.

Indexed as

CannabisHypersensitivityOccupational ExposureAdultCross-Sectional StudiesDustFemaleHumansMaleRespiration DisordersDustallergic diseaseCannabisoccupational asthmaoccupational hazardsrespiratory symptoms

Identifiers

PMID32459852
PMCPMC7407609
OpenAlexW3031086016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.