Evidence map›Paper›PMID 32459663›Full record

ArticleThe Journal of clinical investigation2020

COVID-19, microangiopathy, hemostatic activation, and complement.

Wen-Chao Song, Garret A FitzGerald

Abstract read
In one paragraph

Article in The Journal of clinical investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wen-Chao SongDepartment of Systems Pharmacology and Translational Therapeutics.
Garret A FitzGeraldDepartment of Systems Pharmacology and Translational Therapeutics.

Funding

Clinical and Translational Science Coordinating CenterU54TR000123 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2017
$14.2M
Pathogenesis and therapy of dense deposit disease in a mouse modelR01AI085596 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2010 to 2019
$3.5M
MASPs as therapeutic targets in complement-mediated diseasesR01AI146162 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2020 to 2024
$2.9M
Atherosclerosis, Prostaglandin Inhibition and Checkpoint BlockadeR01HL141912 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2019 to 2022
$2.6M
Complement dysregulation and atypical hemolytic uremic syndromeR01AI117410 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SONG, WENCHAO · 2015 to 2019
$2.0M
NCATS NIH HHS U54 TR000123NHLBI NIH HHS R01 HL141912NIAID NIH HHS R01 AI085596NIAID NIH HHS R01 AI117410NIAID NIH HHS R01 AI146162
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BetacoronavirusComplement ActivationComplement System ProteinsCoronavirus InfectionsCOVID-19HemostasisHumansNecrosisPandemicsPhenotypePneumonia, ViralRespiratory Distress SyndromeSARS-CoV-2ThrombosisThrombotic MicroangiopathiesComplement System Proteins

Identifiers

PMID32459663
PMCPMC7410042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.