Evidence map›Paper›PMID 32459452›Full record

SynthesisInternational braz j urol : official journal of the Brazilian Society of Urology

Long term outcomes of one-stage augmentation anterior urethroplasty: a systematic review and meta-analysis.

Cooper R Benson, Gen Li, Steven B Brandes

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  9. [Urethral reconstruction].Urologie (Heidelberg, Germany) · 2024
    Review
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  18. The Story of Female Urethral Stricture - "To a man with a hammer, everything looks like a nail".International braz j urol : official journal of the Brazilian Society of Urology
    Article
  19. Re: Long term outcomes of one-stage augmentation anterior urethroplasty: a systematic review and meta-analysis.International braz j urol : official journal of the Brazilian Society of Urology
    Article
  20. Re: Long term outcomes of one-stage augmentation anterior urethroplasty: a systematic review and meta-analysis.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Cooper R BensonDepartment of Urology, Columbia University Medical Center, New York, NY, USA.
Gen LiDepartment of Biostatistics, Columbia University Medical Center, New York, NY, USA.
Steven B BrandesDepartment of Urology, Columbia University Medical Center, New York, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe objective is to summarize and characterize the long-term success of anterior augmentation urethroplasty (AU) in published series. The current literature on AU consists largely of retrospective series reporting intermediate follow-up and incompletely characterize the long term outcomes of AU. MATERIALS AND

methodsA systematic literature review was performed consistent with PRISMA guidelines to characterize long-term outcomes of AU with a minimum upper limit follow-up of 100 months. Penile/preputial skin flaps and graft and oral mucosal graft urethroplasties were included. The primary outcome was stricture-free survival for one-stage AU. Secondary analysis evaluated differences in outcomes based on two failure definitions: the need for intervention versus presence of recurrent stricture on cystoscopy or urethrography. Hazard rates were induced from the reported failure rates of one-stage AU and fixed and random effect models were fitted to the data. Additional subset analysis, removing potential confounders (lichen sclerosus, hypospadias and penile skin graft), was performed.

resultsTen studies met inclusion criteria, and two studies reported separate outcomes for grafts and flaps, and thus were included separately in the analysis. The mean hazard rate across all studies was 0.0044, the corresponding survival rates at 1 year 0.948, 5 years 0.766, 10 years 0.587, and 15 years 0.45. Subset analysis of the 4 select and homogeneous studies noted 1, 5, 10, and 15 years survival rates of 0.97, 0.96, 0.74, and 0.63, respectively.

conclusionsThe long-term success rates of augmentation urethroplasty are appear to be worse than previously appreciated and patients should be counseled accordingly. Available at. https://www.intbrazjurol.com.br/pdf/aop/2019-0242RW.pdf.

Indexed as

Urethral StrictureHumansMaleMouth MucosaRetrospective StudiesTreatment OutcomeUrethraUrologic Surgical Procedures, MaleCystoscopySystematic Review [Publication Type]Urethral Stricture

Identifiers

PMID32459452
PMCPMC7857757

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.